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eF-site ID
|
2zhx-A |
|
PDB Code
|
2zhx |
|
Chain
|
A |
|
click to enlarge
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Title
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Crystal structure of Uracil-DNA Glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor |
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Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
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Compound
|
Uracil-DNA glycosylase |
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Source
|
(UNGI_BPPB2) |
|
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Sequence
|
A: |
ARPLSELVERGWAAALEPVADQVAHMGQFLRAEIAAGRRY
LPAGSNVLRAFTFPFDNVRVLIVGQDPYPTPGHAVGLSFS
VAPDVRPWPRSLANIFDEYTADLGYPLPSNGDLTPWAQRG
VLLLNRVLTVRPSNPASHRGKGWEAVTECAIRALAARAAP
LVAILWGRDASTLKPMLAAGNCVAIESPHPSPLSASRGFF
GSRPFSRANELLVGMGAEPIDWRLP
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
61-70 |
| type |
prosite |
| sequence |
RVLIVGQDPY
|
| description |
U_DNA_GLYCOSYLASE Uracil-DNA glycosylase signature. RVLIvGQDPY
|
| source |
prosite : PS00130
|
|
|
2)
|
chain |
A |
| residue |
68 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
Proton acceptor => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
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