eF-site ID 2z4y-B PDB Code 2z4y Chain B click to enlarge Title S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-252 Classification TRANSFERASE/TRANSFERASE INHIBITOR Compound Geranylgeranyl pyrophosphate synthetase Source null (GGPPS_YEAST) Sequence B:  NKMEAKIDELINNDPVWSSQNESLISKPYNHILLIVQINR VMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQT TSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLI TIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMN KTGGLFRLTLRLMEALSPSSLVPFINLLGIIYQIRDDYLN LKDFGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILR ILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVNMI KN Description Functional site 1) chain B residue 214 type sequence D description BINDING SITE FOR RESIDUE MG B 1301 source : AC1 2) chain B residue 238 type sequence K description BINDING SITE FOR RESIDUE MG B 1301 source : AC1 3) chain B residue 80 type sequence D description BINDING SITE FOR RESIDUE 252 B 1203 source : AC4 4) chain B residue 89 type sequence R description BINDING SITE FOR RESIDUE 252 B 1203 source : AC4 5) chain B residue 143 type sequence L description BINDING SITE FOR RESIDUE 252 B 1203 source : AC4 6) chain B residue 144 type sequence H description BINDING SITE FOR RESIDUE 252 B 1203 source : AC4 7) chain B residue 174 type sequence K description BINDING SITE FOR RESIDUE 252 B 1203 source : AC4 8) chain B residue 211 type sequence Q description BINDING SITE FOR RESIDUE 252 B 1203 source : AC4 9) chain B residue 214 type sequence D description BINDING SITE FOR RESIDUE 252 B 1203 source : AC4 10) chain B residue 238 type sequence K description BINDING SITE FOR RESIDUE 252 B 1203 source : AC4 11) chain B residue 73 type BINDING sequence H description BINDING => ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI1 12) chain B residue 89 type BINDING sequence R description BINDING => ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI1 13) chain B residue 90 type BINDING sequence R description BINDING => ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI1 14) chain B residue 174 type BINDING sequence K description BINDING => ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI1 15) chain B residue 175 type BINDING sequence T description BINDING => ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 211 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI1 17) chain B residue 218 type BINDING sequence N description BINDING => ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 238 type BINDING sequence K description BINDING => ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 80 type BINDING sequence D description BINDING => ECO:0000269|PubMed:16554305, ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI2 20) chain B residue 84 type BINDING sequence D description BINDING => ECO:0000269|PubMed:16554305, ECO:0000269|PubMed:17535895 source Swiss-Prot : SWS_FT_FI2 21) chain B residue 112 type SITE sequence Y description Important for determining product chain length source Swiss-Prot : SWS_FT_FI4

Display surface Download Links