|
|
eF-site ID
|
2ywb-A |
|
PDB Code
|
2ywb |
|
Chain
|
A |
|
click to enlarge
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Title
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Crystal structure of GMP synthetase from Thermus thermophilus |
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Classification
|
LIGASE |
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Compound
|
GMP synthase [glutamine-hydrolyzing] |
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Source
|
null (GUAA_THET8) |
|
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Sequence
|
A: |
MVLVLDFGSQYTRLIARRLRELRAFSLILPGDAPLEEVLK
HRPQALILSGGPRSVFDPDAPRPDPRLFSSGLPLLGICYG
MQLLAQELGGRVERAEYGKALLTRHEGPLFRGLEGEVQVW
MSHQDAVTAPPPGWRVVAETEENPVAAIASPDGRAYGVQF
HPEVAHTPKGMQILENFLELAGVKRDWTPEHVLEELLREV
RERAGKDRVLLAVSGGVDSSTLALLLAKAGVDHLAVFVDH
GLLRLGEREEVEGALRALGVNLLVVDAKERFLKALKGVED
PEEKRKIIGREFVAAFSQVARERGPFRFLAQGTLYPDVIE
GLPEDLEFELLEPFRLLFKDEVRELALLLGLPDTLRLRHP
FPGPGLAVRVLGEVTEERLEILRRADDIFTSLLREWGLYE
KVAQALAVLTPVGYVLALRAVTTEDFMTADWARLPLEFLD
EAARRITRRVPEIGRVVYDLTSKPPATIEWE
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
78 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Nucleophile => ECO:0000255|HAMAP-Rule:MF_00344
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
164 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00344
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
166 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00344
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
217 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00344
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|