eF-site ID 2yv9-AB PDB Code 2yv9 Chain A, B click to enlarge Title Crystal structure of the CLIC homologue EXC-4 from c. elegans Classification METAL TRANSPORT Compound Chloride intracellular channel exc-4 Source Caenorhabditis elegans (EXC4_CAEEL) Sequence A:  AMAEAYQIQSNGDPQSKPLLELYVKASGIDARRIGADLFC QEFWMELYALYEIGVARVEVKTVNVNSEAFKKNFLGAQPP IMIEEEKELTYTDNREIEGRIFHLAKEFNVPLFEKDPSAE KRIENLYRNFKLFLRAKVEFDKGKKEPSRVEDLPAQIKVH YNRVCEQLSNIDQLLSERKSRYLLGNSMTEYDCELMPRLH HIRIIGLSLLGFDIPHNFTHLWAYILTAYRTAAFIESCPA DQDIIHHYKEQMNLFTNQRETLQSPTKTHTIPEKVLSDIR VKGLA B:  SKPLLELYVKASGIDARRIGADLFCQEFWMELYALYEIGV ARVEVKTVNVNSEAFKKNFLGAQPPIMIEEEKELTYTDNR EIEGRIFHLAKEFNVPLFEKDPSAEKRIENLYRNFKLFLR AKVEFDKSRVEDLPAQIKVHYNRVCEQLSNIDQLLSERKS RYLLGNSMTEYDCELMPRLHHIRIIGLSLLGFDIPHNFTH LWAYILTAYRTAAFIESCPADQDIIHHYKEQMNLFTNQRE TLQSPTKTHTIPEKVLSDIRVKGLAP Description Functional site 1) chain A residue 77 type sequence Q description BINDING SITE FOR RESIDUE CA A 1002 source : AC1 2) chain A residue 79 type sequence P description BINDING SITE FOR RESIDUE CA A 1002 source : AC1 3) chain A residue 91 type sequence T description BINDING SITE FOR RESIDUE CA A 1002 source : AC1 4) chain A residue 93 type sequence N description BINDING SITE FOR RESIDUE CA A 1002 source : AC1 5) chain B residue 77 type sequence Q description BINDING SITE FOR RESIDUE CA B 1001 source : AC2 6) chain B residue 79 type sequence P description BINDING SITE FOR RESIDUE CA B 1001 source : AC2 7) chain B residue 91 type sequence T description BINDING SITE FOR RESIDUE CA B 1001 source : AC2 8) chain B residue 93 type sequence N description BINDING SITE FOR RESIDUE CA B 1001 source : AC2 9) chain A residue 37-57 type TRANSMEM sequence LFCQEFWMELYALYEIGVARV description Helical; Note=After insertion into the membrane => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 10) chain B residue 37-57 type TRANSMEM sequence LFCQEFWMELYALYEIGVARV description Helical; Note=After insertion into the membrane => ECO:0000255 source Swiss-Prot : SWS_FT_FI1

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