eF-site ID 2yqj-B PDB Code 2yqj Chain B click to enlarge Title Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the reaction-completed form Classification TRANSFERASE Compound UDP-N-acetylglucosamine pyrophosphorylase Source Candida albicans (Yeast) (UAP1_CANAL) Sequence B:  VKSQQQIIDSFKQANQDQLFQYYDSLTIDQQQEFIDQLST IEEPAKLISTVEQARNFTQLPNEQTASTLDLSKDILQNWT ELGLKAIGNGEVAVLLMAGGQGTRLGSSAPKGCFNIELPS QKSLFQIQAEKILKIEQLAQQYLKSTKKPIINWYIMTSGP TRNATESFFIENNYFGLNSHQVIFFNQGTLPCFNLQGNKI LLELKNSICQSPDGNGGLYKALKDNGILDDLNSKGIKHIH MYCVDNCLVKVADPIFIGFAIAKKFDLATKVVRKRDANES VGLIVLDQDNQKPCVIEYSEISQELANKKDPQDSSKLFLR AANIVNHYYSVEFLNKMIPKWISSQKYLPFHIAKKKIPSL NLEFYKPTEPNGIKLEQFIFDVFPSVELNKFGCLEVDRLD EFSPLKNADGAKNDTPTTCRNHYLERSSKWVIQNGGVIDN QGLVEVDSKTSYGGEGLEFVNGKHFKNGDII Description Functional site 1) chain B residue 328 type sequence K description BINDING SITE FOR RESIDUE SO4 B 2102 source : AC4 2) chain B residue 332 type sequence R description BINDING SITE FOR RESIDUE SO4 B 2102 source : AC4 3) chain B residue 109 type sequence M description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 4) chain B residue 111 type sequence G description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 5) chain B residue 112 type sequence G description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 6) chain B residue 116 type sequence R description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 7) chain B residue 168 type sequence M description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 8) chain B residue 199 type sequence Q description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 9) chain B residue 224 type sequence P description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 10) chain B residue 226 type sequence G description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 11) chain B residue 227 type sequence N description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 12) chain B residue 255 type sequence C description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 13) chain B residue 256 type sequence V description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 14) chain B residue 257 type sequence D description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 15) chain B residue 293 type sequence V description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 16) chain B residue 294 type sequence G description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 17) chain B residue 309 type sequence E description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 18) chain B residue 310 type sequence Y description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 19) chain B residue 335 type sequence N description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 20) chain B residue 337 type sequence V description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 21) chain B residue 393 type sequence F description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 22) chain B residue 395 type sequence F description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 23) chain B residue 417 type sequence F description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 24) chain B residue 421 type sequence K description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 25) chain B residue 6 type sequence Q description BINDING SITE FOR RESIDUE GOL A 1301 source : AC7 26) chain B residue 226 type BINDING sequence G description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 27) chain B residue 257 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 28) chain B residue 389 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 29) chain B residue 109 type BINDING sequence M description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 30) chain B residue 123 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 31) chain B residue 199 type BINDING sequence Q description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 32) chain B residue 227 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 33) chain B residue 421 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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