eF-site ID 2yqj-AB PDB Code 2yqj Chain A, B click to enlarge Title Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the reaction-completed form Classification TRANSFERASE Compound UDP-N-acetylglucosamine pyrophosphorylase Source null (UAP1_CANAL) Sequence A:  VKSQQQIIDSFKQANQDQLFQYYDSLTIDQQQEFIDQLST IEEPAKLISTVEQAIRNFTQLPNEQTASTLDLSKDILQNW TELGLKAIGNGEVAVLLMAGGQGTRLGSSAPKGCFNIELP SQKSLFQIQAEKILKIEQLAQQYLKSTKKPIINWYIMTSG PTRNATESFFIENNYFGLNSHQVIFFNQGTLPCFNLQGNK ILLELKNSICQSPDGNGGLYKALKDNGILDDLNSKGIKHI HMYCVDNCLVKVADPIFIGFAIAKKFDLATKVVRKRDANE SVGLIVLDQDNQKPCVIEYSEISQELANKKDPQDSSKLFL RAANIVNHYYSVEFLNKMIPKWISSQKYLPFHIAKKKIPS LNLGEFYKPTEPNGIKLEQFIFDVFPSVELNKFGCLEVDR LDEFSPLKNADGAKNDTPTTCRNHYLERSSKWVIQNGGVI DNQGLVEVDSKTSYGGEGLEFVNGKHFKNGDII B:  VKSQQQIIDSFKQANQDQLFQYYDSLTIDQQQEFIDQLST IEEPAKLISTVEQARNFTQLPNEQTASTLDLSKDILQNWT ELGLKAIGNGEVAVLLMAGGQGTRLGSSAPKGCFNIELPS QKSLFQIQAEKILKIEQLAQQYLKSTKKPIINWYIMTSGP TRNATESFFIENNYFGLNSHQVIFFNQGTLPCFNLQGNKI LLELKNSICQSPDGNGGLYKALKDNGILDDLNSKGIKHIH MYCVDNCLVKVADPIFIGFAIAKKFDLATKVVRKRDANES VGLIVLDQDNQKPCVIEYSEISQELANKKDPQDSSKLFLR AANIVNHYYSVEFLNKMIPKWISSQKYLPFHIAKKKIPSL NLEFYKPTEPNGIKLEQFIFDVFPSVELNKFGCLEVDRLD EFSPLKNADGAKNDTPTTCRNHYLERSSKWVIQNGGVIDN QGLVEVDSKTSYGGEGLEFVNGKHFKNGDII Description Functional site 1) chain A residue 114 type sequence G description BINDING SITE FOR RESIDUE SO4 A 1101 source : AC1 2) chain A residue 115 type sequence T description BINDING SITE FOR RESIDUE SO4 A 1101 source : AC1 3) chain A residue 116 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1101 source : AC1 4) chain A residue 285 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1102 source : AC2 5) chain A residue 328 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1102 source : AC2 6) chain A residue 332 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1102 source : AC2 7) chain A residue 74 type sequence N description BINDING SITE FOR RESIDUE MG A 1201 source : AC3 8) chain A residue 77 type sequence T description BINDING SITE FOR RESIDUE MG A 1201 source : AC3 9) chain B residue 328 type sequence K description BINDING SITE FOR RESIDUE SO4 B 2102 source : AC4 10) chain B residue 332 type sequence R description BINDING SITE FOR RESIDUE SO4 B 2102 source : AC4 11) chain A residue 109 type sequence M description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 12) chain A residue 111 type sequence G description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 13) chain A residue 112 type sequence G description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 14) chain A residue 116 type sequence R description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 15) chain A residue 168 type sequence M description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 16) chain A residue 199 type sequence Q description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 17) chain A residue 224 type sequence P description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 18) chain A residue 226 type sequence G description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 19) chain A residue 227 type sequence N description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 20) chain A residue 255 type sequence C description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 21) chain A residue 256 type sequence V description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 22) chain A residue 293 type sequence V description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 23) chain A residue 294 type sequence G description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 24) chain A residue 309 type sequence E description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 25) chain A residue 310 type sequence Y description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 26) chain A residue 335 type sequence N description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 27) chain A residue 337 type sequence V description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 28) chain A residue 393 type sequence F description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 29) chain A residue 395 type sequence F description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 30) chain A residue 417 type sequence F description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 31) chain A residue 421 type sequence K description BINDING SITE FOR RESIDUE UD1 A 1001 source : AC5 32) chain B residue 109 type sequence M description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 33) chain B residue 111 type sequence G description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 34) chain B residue 112 type sequence G description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 35) chain B residue 116 type sequence R description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 36) chain B residue 168 type sequence M description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 37) chain B residue 199 type sequence Q description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 38) chain B residue 224 type sequence P description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 39) chain B residue 226 type sequence G description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 40) chain B residue 227 type sequence N description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 41) chain B residue 255 type sequence C description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 42) chain B residue 256 type sequence V description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 43) chain B residue 257 type sequence D description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 44) chain B residue 293 type sequence V description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 45) chain B residue 294 type sequence G description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 46) chain B residue 309 type sequence E description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 47) chain B residue 310 type sequence Y description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 48) chain B residue 335 type sequence N description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 49) chain B residue 337 type sequence V description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 50) chain B residue 393 type sequence F description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 51) chain B residue 395 type sequence F description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 52) chain B residue 417 type sequence F description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 53) chain B residue 421 type sequence K description BINDING SITE FOR RESIDUE UD1 B 2001 source : AC6 54) chain A residue 196 type sequence F description BINDING SITE FOR RESIDUE GOL A 1301 source : AC7 55) chain A residue 237 type sequence N description BINDING SITE FOR RESIDUE GOL A 1301 source : AC7 56) chain B residue 6 type sequence Q description BINDING SITE FOR RESIDUE GOL A 1301 source : AC7 57) chain A residue 199 type BINDING sequence Q description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 58) chain A residue 226 type BINDING sequence G description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 59) chain A residue 257 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 60) chain A residue 389 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 61) chain B residue 109 type BINDING sequence M description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 62) chain B residue 123 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 63) chain B residue 226 type BINDING sequence G description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 64) chain B residue 257 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 65) chain B residue 389 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 66) chain B residue 199 type BINDING sequence Q description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 67) chain A residue 109 type BINDING sequence M description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 68) chain A residue 123 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:Q9M9P3 source Swiss-Prot : SWS_FT_FI1 69) chain B residue 227 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 70) chain B residue 421 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 71) chain A residue 227 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 72) chain A residue 421 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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