|
eF-site ID
|
2ypt-F |
PDB Code
|
2ypt |
Chain
|
F |
|
click to enlarge
|
|
Title
|
Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 mutant (E336A) in complex with a synthetic CSIM tetrapeptide from the C-terminus of prelamin A |
Classification
|
HYDROLASE/PEPTIDE |
Compound
|
CAAX PRENYL PROTEASE 1 HOMOLOG |
Source
|
Homo sapiens (Human) (LMNA_HUMAN) |
|
Sequence
|
F: |
CSI
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
F |
residue |
662 |
type |
|
sequence |
S
|
description |
BINDING SITE FOR RESIDUE ZN A 600
|
source |
: AC1
|
|
2)
|
chain |
F |
residue |
661 |
type |
MOD_RES |
sequence |
C
|
description |
Cysteine methyl ester => ECO:0000269|PubMed:8175923, ECO:0000269|PubMed:9030603
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
3)
|
chain |
F |
residue |
661 |
type |
LIPID |
sequence |
C
|
description |
S-farnesyl cysteine => ECO:0000269|PubMed:8175923, ECO:0000269|PubMed:9030603
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|