eF-site ID 2ypd-AB PDB Code 2ypd Chain A, B click to enlarge Title Crystal structure of the Jumonji domain of human Jumonji domain containing 1C protein Classification OXIDOREDUCTASE Compound PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C Source Homo sapiens (Human) (JHD2C_HUMAN) Sequence A:  MIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVS GVHKKMNISLWKAESISLDFGDHQADLLNCKDSIISNANV KEFWDGFEEVSKRETVVLKLKDWPSGEDFKTMMPARYEDL LKSLPLPEYCNPEGKFNLASHLPGFFVRGPRLCSAYGVVA AKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGIL KKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIRE FLQKISKEQGHDPIRDQSWYVNKKLRQRLLEEYGVRTCTL IQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVES FHLTQEL B:  MIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVS GVHKKMNISLWKAESISLDFGDHQADLLNCKDSIISNANV KEFWDGFEEVSKRETVVLKLKDWPSGEDFKTMMPARYEDL LKSLPLPEYCNPEGKFNLASHLPGFFVGPRLCSAYGVVAA KDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILK KFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREF LQKISKEQGHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLI QFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESF HLTQEL Description (1)  PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (E.C.1.14.11.-) Functional site 1) chain A residue 2163 type sequence C description BINDING SITE FOR RESIDUE EMT A 3498 source : AC1 2) chain A residue 2166 type sequence H description BINDING SITE FOR RESIDUE EMT A 3498 source : AC1 3) chain A residue 2446 type sequence R description BINDING SITE FOR RESIDUE EMT A 3498 source : AC1 4) chain A residue 2447 type sequence T description BINDING SITE FOR RESIDUE EMT A 3498 source : AC1 5) chain A residue 2448 type sequence C description BINDING SITE FOR RESIDUE EMT A 3498 source : AC1 6) chain A residue 2166 type sequence H description BINDING SITE FOR RESIDUE EMT A 3499 source : AC2 7) chain A residue 2393 type sequence I description BINDING SITE FOR RESIDUE EMT A 3499 source : AC2 8) chain A residue 2446 type sequence R description BINDING SITE FOR RESIDUE EMT A 3499 source : AC2 9) chain A residue 2448 type sequence C description BINDING SITE FOR RESIDUE EMT A 3499 source : AC2 10) chain A residue 2184 type sequence E description BINDING SITE FOR RESIDUE EMT A 3500 source : AC3 11) chain A residue 2185 type sequence C description BINDING SITE FOR RESIDUE EMT A 3500 source : AC3 12) chain A residue 2188 type sequence Q description BINDING SITE FOR RESIDUE EMT A 3500 source : AC3 13) chain B residue 2166 type sequence H description BINDING SITE FOR RESIDUE EMT B 3498 source : AC4 14) chain B residue 2393 type sequence I description BINDING SITE FOR RESIDUE EMT B 3498 source : AC4 15) chain B residue 2446 type sequence R description BINDING SITE FOR RESIDUE EMT B 3498 source : AC4 16) chain B residue 2448 type sequence C description BINDING SITE FOR RESIDUE EMT B 3498 source : AC4 17) chain B residue 2163 type sequence C description BINDING SITE FOR RESIDUE EMT B 3499 source : AC5 18) chain B residue 2166 type sequence H description BINDING SITE FOR RESIDUE EMT B 3499 source : AC5 19) chain B residue 2446 type sequence R description BINDING SITE FOR RESIDUE EMT B 3499 source : AC5 20) chain B residue 2447 type sequence T description BINDING SITE FOR RESIDUE EMT B 3499 source : AC5 21) chain B residue 2448 type sequence C description BINDING SITE FOR RESIDUE EMT B 3499 source : AC5 22) chain B residue 2184 type sequence E description BINDING SITE FOR RESIDUE EMT B 3500 source : AC6 23) chain B residue 2185 type sequence C description BINDING SITE FOR RESIDUE EMT B 3500 source : AC6 24) chain B residue 2188 type sequence Q description BINDING SITE FOR RESIDUE EMT B 3500 source : AC6 25) chain B residue 2190 type sequence Q description BINDING SITE FOR RESIDUE EMT B 3500 source : AC6 26) chain A residue 2225 type sequence C description BINDING SITE FOR RESIDUE EMT A 3501 source : AC7 27) chain A residue 2260 type sequence K description BINDING SITE FOR RESIDUE EMT A 3501 source : AC7 28) chain A residue 2331 type sequence G description BINDING SITE FOR RESIDUE EMT A 3501 source : AC7 29) chain A residue 2332 type sequence T description BINDING SITE FOR RESIDUE EMT A 3501 source : AC7 30) chain A residue 2334 type sequence N description BINDING SITE FOR RESIDUE EMT A 3501 source : AC7 31) chain A residue 2260 type sequence K description BINDING SITE FOR RESIDUE EMT A 3502 source : AC8 32) chain A residue 2263 type sequence D description BINDING SITE FOR RESIDUE EMT A 3502 source : AC8 33) chain A residue 2317 type sequence C description BINDING SITE FOR RESIDUE EMT A 3502 source : AC8 34) chain B residue 2263 type sequence D description BINDING SITE FOR RESIDUE EMT B 3501 source : AC9 35) chain B residue 2315 type sequence R description BINDING SITE FOR RESIDUE EMT B 3501 source : AC9 36) chain B residue 2317 type sequence C description BINDING SITE FOR RESIDUE EMT B 3501 source : AC9 37) chain B residue 2476 type sequence Q description BINDING SITE FOR RESIDUE EMT B 3501 source : AC9 38) chain B residue 2478 type sequence T description BINDING SITE FOR RESIDUE EMT B 3501 source : AC9 39) chain B residue 2317 type sequence C description BINDING SITE FOR RESIDUE EMT B 3502 source : BC1 40) chain B residue 2333 type sequence T description BINDING SITE FOR RESIDUE EMT B 3502 source : BC1 41) chain B residue 2344 type sequence N description BINDING SITE FOR RESIDUE EMT B 3502 source : BC1 42) chain B residue 2476 type sequence Q description BINDING SITE FOR RESIDUE EMT B 3502 source : BC1 43) chain A residue 2317 type sequence C description BINDING SITE FOR RESIDUE EMT A 3503 source : BC2 44) chain A residue 2333 type sequence T description BINDING SITE FOR RESIDUE EMT A 3503 source : BC2 45) chain A residue 2476 type sequence Q description BINDING SITE FOR RESIDUE EMT A 3503 source : BC2 46) chain B residue 2274 type sequence M description BINDING SITE FOR RESIDUE NA B 3503 source : BC3 47) chain B residue 2275 type sequence P description BINDING SITE FOR RESIDUE NA B 3503 source : BC3 48) chain B residue 2276 type sequence A description BINDING SITE FOR RESIDUE NA B 3503 source : BC3 49) chain B residue 2277 type sequence R description BINDING SITE FOR RESIDUE NA B 3503 source : BC3 50) chain A residue 2274 type sequence M description BINDING SITE FOR RESIDUE NA A 3504 source : BC4 51) chain A residue 2276 type sequence A description BINDING SITE FOR RESIDUE NA A 3504 source : BC4 52) chain A residue 2277 type sequence R description BINDING SITE FOR RESIDUE NA A 3504 source : BC4 53) chain A residue 2336 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538 source Swiss-Prot : SWS_FT_FI1 54) chain A residue 2338 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538 source Swiss-Prot : SWS_FT_FI1 55) chain A residue 2466 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538 source Swiss-Prot : SWS_FT_FI1 56) chain B residue 2336 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538 source Swiss-Prot : SWS_FT_FI1 57) chain B residue 2338 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538 source Swiss-Prot : SWS_FT_FI1 58) chain B residue 2466 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538 source Swiss-Prot : SWS_FT_FI1

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