eF-site ID 2ypa-ABCD PDB Code 2ypa Chain A, B, C, D click to enlarge Title Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA Classification IMMUNE SYSTEM Compound T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 Source Homo sapiens (Human) (2YPA) Sequence A:  PHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDK KLSKNEILRLAMKYINFLAKLLNDQEE B:  EKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLK SDKAQTKLLILQQAVQVILGLEQQVRERNLNPK C:  CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGR RLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMR VKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIY EWTKIN D:  DVMVVGEPTLMGGEFGDEDERLITRLENTQ Description (1)  T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, TRANSCRIPTION FACTOR E2-ALPHA, RHOMBOTIN-2, LIM DOMAIN-BINDING PROTEIN 1 Functional site 1) chain C residue 122 type sequence C description BINDING SITE FOR RESIDUE ZN C 1156 source : AC1 2) chain C residue 125 type sequence C description BINDING SITE FOR RESIDUE ZN C 1156 source : AC1 3) chain C residue 144 type sequence C description BINDING SITE FOR RESIDUE ZN C 1156 source : AC1 4) chain C residue 147 type sequence D description BINDING SITE FOR RESIDUE ZN C 1156 source : AC1 5) chain C residue 94 type sequence C description BINDING SITE FOR RESIDUE ZN C 1157 source : AC2 6) chain C residue 97 type sequence C description BINDING SITE FOR RESIDUE ZN C 1157 source : AC2 7) chain C residue 116 type sequence H description BINDING SITE FOR RESIDUE ZN C 1157 source : AC2 8) chain C residue 119 type sequence C description BINDING SITE FOR RESIDUE ZN C 1157 source : AC2 9) chain C residue 57 type sequence C description BINDING SITE FOR RESIDUE ZN C 1158 source : AC3 10) chain C residue 60 type sequence C description BINDING SITE FOR RESIDUE ZN C 1158 source : AC3 11) chain C residue 80 type sequence C description BINDING SITE FOR RESIDUE ZN C 1158 source : AC3 12) chain C residue 83 type sequence D description BINDING SITE FOR RESIDUE ZN C 1158 source : AC3 13) chain C residue 30 type sequence C description BINDING SITE FOR RESIDUE ZN C 1159 source : AC4 14) chain C residue 33 type sequence C description BINDING SITE FOR RESIDUE ZN C 1159 source : AC4 15) chain C residue 51 type sequence H description BINDING SITE FOR RESIDUE ZN C 1159 source : AC4 16) chain C residue 54 type sequence C description BINDING SITE FOR RESIDUE ZN C 1159 source : AC4 17) chain C residue 30-64 type prosite sequence CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRL description LIM_DOMAIN_1 LIM zinc-binding domain signature. CggCqqnigdryflkaidqy.....WHedClsCdlCgcrL source prosite : PS00478 18) chain C residue 94-129 type prosite sequence CASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHF description LIM_DOMAIN_1 LIM zinc-binding domain signature. CggCqqnigdryflkaidqy.....WHedClsCdlCgcrL source prosite : PS00478

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