eF-site ID 2yja-B PDB Code 2yja Chain B click to enlarge Title Stapled Peptides binding to Estrogen Receptor alpha. Classification HORMONE RECEPTOR/PEPTIDE Compound STAPLED PEPTIDE Source null (ESR1_HUMAN) Sequence B:  SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMG LLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWL EILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEI FDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL AQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEML DAHRL Description (1)  STAPLED PEPTIDE, ESTROGEN RECEPTOR Functional site 1) chain B residue 343 type sequence M description BINDING SITE FOR RESIDUE EST B 1550 source : AC1 2) chain B residue 346 type sequence L description BINDING SITE FOR RESIDUE EST B 1550 source : AC1 3) chain B residue 353 type sequence E description BINDING SITE FOR RESIDUE EST B 1550 source : AC1 4) chain B residue 387 type sequence L description BINDING SITE FOR RESIDUE EST B 1550 source : AC1 5) chain B residue 394 type sequence R description BINDING SITE FOR RESIDUE EST B 1550 source : AC1 6) chain B residue 404 type sequence F description BINDING SITE FOR RESIDUE EST B 1550 source : AC1 7) chain B residue 421 type sequence M description BINDING SITE FOR RESIDUE EST B 1550 source : AC1 8) chain B residue 524 type sequence H description BINDING SITE FOR RESIDUE EST B 1550 source : AC1 9) chain B residue 525 type sequence L description BINDING SITE FOR RESIDUE EST B 1550 source : AC1 10) chain B residue 537 type MOD_RES sequence Y description Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 source Swiss-Prot : SWS_FT_FI1 11) chain B residue 447 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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