eF-site ID 2yho-H PDB Code 2yho Chain H click to enlarge Title The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor Classification LIGASE Compound E3 UBIQUITIN-PROTEIN LIGASE MYLIP Source Homo sapiens (Human) (UB2D1_HUMAN) Sequence H:  MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGP PDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINS NGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV PDIAQIYKSDKEKYNRHAREWTQKYAM Description Functional site 1) chain H residue 67 type sequence I description BINDING SITE FOR RESIDUE ACT H 1148 source : AC9 2) chain H residue 84 type sequence I description BINDING SITE FOR RESIDUE ACT H 1148 source : AC9 3) chain H residue 5 type sequence R description BINDING SITE FOR RESIDUE ACT H 1149 source : BC2 4) chain H residue 8 type sequence K description BINDING SITE FOR RESIDUE ACT H 1149 source : BC2 5) chain H residue 57 type sequence P description BINDING SITE FOR RESIDUE ACT H 1150 source : BC7 6) chain H residue 58 type sequence T description BINDING SITE FOR RESIDUE ACT H 1150 source : BC7 7) chain H residue 85 type ACT_SITE sequence C description Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133 source Swiss-Prot : SWS_FT_FI1

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