eF-site ID 2yho-A
PDB Code 2yho
Chain A

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Title The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
Classification LIGASE
Compound E3 UBIQUITIN-PROTEIN LIGASE MYLIP
Source Homo sapiens (Human) (UB2D1_HUMAN)
Sequence A:  RVLQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCESC
AAQLQSCPVCRSRVEHVQHVYLPTHTS
Description


Functional site

1) chain A
residue 387
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1001
source : AC1

2) chain A
residue 390
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1001
source : AC1

3) chain A
residue 408
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1001
source : AC1

4) chain A
residue 411
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1001
source : AC1

5) chain A
residue 402
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1002
source : AC2

6) chain A
residue 404
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 1002
source : AC2

7) chain A
residue 418
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1002
source : AC2

8) chain A
residue 421
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1002
source : AC2

9) chain A
residue 383
type
sequence E
description BINDING SITE FOR RESIDUE ACT A 1439
source : BC6

10) chain A
residue 384
type
sequence A
description BINDING SITE FOR RESIDUE ACT A 1439
source : BC6

11) chain A
residue 386
type
sequence L
description BINDING SITE FOR RESIDUE ACT A 1439
source : BC6

12) chain A
residue 404
type
sequence H
description BINDING SITE FOR RESIDUE ACT A 1440
source : BC8


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