eF-site ID 2yhn-AB
PDB Code 2yhn
Chain A, B

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Title The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
Classification LIGASE
Compound E3 UBIQUITIN-PROTEIN LIGASE MYLIP
Source Homo sapiens (Human) (MYLIP_HUMAN)
Sequence A:  VLQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCESCA
AQLQSCPVCRSRVEHVQHVYLPTH
B:  VLQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCESCA
AQLQSCPVCRSRVEHVQHVYLPTH
Description


Functional site

1) chain A
residue 387
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1001
source : AC1

2) chain A
residue 390
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1001
source : AC1

3) chain A
residue 408
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1001
source : AC1

4) chain A
residue 411
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1001
source : AC1

5) chain A
residue 402
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1002
source : AC2

6) chain A
residue 404
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 1002
source : AC2

7) chain A
residue 418
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1002
source : AC2

8) chain A
residue 421
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1002
source : AC2

9) chain B
residue 387
type
sequence C
description BINDING SITE FOR RESIDUE ZN B 1001
source : AC3

10) chain B
residue 390
type
sequence C
description BINDING SITE FOR RESIDUE ZN B 1001
source : AC3

11) chain B
residue 393
type
sequence E
description BINDING SITE FOR RESIDUE ZN B 1001
source : AC3

12) chain B
residue 408
type
sequence C
description BINDING SITE FOR RESIDUE ZN B 1001
source : AC3

13) chain B
residue 411
type
sequence C
description BINDING SITE FOR RESIDUE ZN B 1001
source : AC3

14) chain B
residue 402
type
sequence C
description BINDING SITE FOR RESIDUE ZN B 1002
source : AC4

15) chain B
residue 404
type
sequence H
description BINDING SITE FOR RESIDUE ZN B 1002
source : AC4

16) chain B
residue 418
type
sequence C
description BINDING SITE FOR RESIDUE ZN B 1002
source : AC4

17) chain B
residue 421
type
sequence C
description BINDING SITE FOR RESIDUE ZN B 1002
source : AC4

18) chain A
residue 387-422
type ZN_FING
sequence CMVCCEEEINSTFCPCGHTVCCESCAAQLQSCPVCR
description RING-type => ECO:0000255|PROSITE-ProRule:PRU00175
source Swiss-Prot : SWS_FT_FI1

19) chain B
residue 387-422
type ZN_FING
sequence CMVCCEEEINSTFCPCGHTVCCESCAAQLQSCPVCR
description RING-type => ECO:0000255|PROSITE-ProRule:PRU00175
source Swiss-Prot : SWS_FT_FI1


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