eF-site ID 2yfe-A PDB Code 2yfe Chain A click to enlarge Title Ligand binding domain of human PPAR gamma in complex with amorfrutin 1 Classification RECEPTOR Compound PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA Source Homo sapiens (Human) (PPARG_HUMAN) Sequence A:  DQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKT TDKSPFVIYDMNSLMMGEDKISKEVAIRIFQGCQFRSVEA VQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAV KFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDN LLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL LQVIKKTETDMSLHPLLQEIYKDL Description Functional site 1) chain A residue 280 type sequence R description BINDING SITE FOR RESIDUE YFE A 999 source : AC1 2) chain A residue 281 type sequence I description BINDING SITE FOR RESIDUE YFE A 999 source : AC1 3) chain A residue 285 type sequence C description BINDING SITE FOR RESIDUE YFE A 999 source : AC1 4) chain A residue 288 type sequence R description BINDING SITE FOR RESIDUE YFE A 999 source : AC1 5) chain A residue 330 type sequence L description BINDING SITE FOR RESIDUE YFE A 999 source : AC1 6) chain A residue 341 type sequence I description BINDING SITE FOR RESIDUE YFE A 999 source : AC1 7) chain A residue 342 type sequence S description BINDING SITE FOR RESIDUE YFE A 999 source : AC1 8) chain A residue 348 type sequence M description BINDING SITE FOR RESIDUE YFE A 999 source : AC1 9) chain A residue 314 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 10) chain A residue 351 type BINDING sequence E description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 11) chain A residue 252 type CROSSLNK sequence M description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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