eF-site ID 2ycw-B PDB Code 2ycw Chain B click to enlarge Title TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CARAZOLOL Classification RECEPTOR Compound BETA-1 ADRENERGIC RECEPTOR Source (ADRB1_MELGA) Sequence B:  AELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRL QTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSF LCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSL MTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKC YQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYR EAKEQIRKIDRASKRKRVMLMREHKALKTLGIIMGVFTLC WLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPII YCRSPDFRKAFKRLLAF Description Functional site 1) chain B residue 117 type sequence W description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 2) chain B residue 121 type sequence D description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 3) chain B residue 201 type sequence F description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 4) chain B residue 207 type sequence Y description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 5) chain B residue 211 type sequence S description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 6) chain B residue 306 type sequence F description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 7) chain B residue 307 type sequence F description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 8) chain B residue 310 type sequence N description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 9) chain B residue 329 type sequence N description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 10) chain B residue 333 type sequence Y description BINDING SITE FOR RESIDUE CAU B 400 source : AC2 11) chain B residue 160 type sequence V description BINDING SITE FOR RESIDUE 2CV A 1361 source : AC4 12) chain B residue 181 type sequence W description BINDING SITE FOR RESIDUE 2CV B 1360 source : AC5 13) chain B residue 206 type sequence A description BINDING SITE FOR RESIDUE 2CV B 1360 source : AC5 14) chain B residue 157 type sequence R description BINDING SITE FOR RESIDUE 2CV B 1362 source : AC6 15) chain B residue 160 type sequence V description BINDING SITE FOR RESIDUE 2CV B 1362 source : AC6 16) chain B residue 111 type sequence S description BINDING SITE FOR RESIDUE NA B 1363 source : AC8 17) chain B residue 192 type sequence C description BINDING SITE FOR RESIDUE NA B 1363 source : AC8 18) chain B residue 195 type sequence D description BINDING SITE FOR RESIDUE NA B 1363 source : AC8 19) chain B residue 198 type sequence C description BINDING SITE FOR RESIDUE NA B 1363 source : AC8 20) chain B residue 104-115 type TOPO_DOM sequence RGTWLWGSFLCE description Extracellular => ECO:0000269|PubMed:18594507 source Swiss-Prot : SWS_FT_FI4 21) chain B residue 180-205 type TOPO_DOM sequence HWWRDEDPQALKCYQDPGCCDFVTNR description Extracellular => ECO:0000269|PubMed:18594507 source Swiss-Prot : SWS_FT_FI4 22) chain B residue 316-320 type TOPO_DOM sequence NRDLV description Extracellular => ECO:0000269|PubMed:18594507 source Swiss-Prot : SWS_FT_FI4 23) chain B residue 39-67 type TRANSMEM sequence QWEAGMSLLMALVVLLIVAGNVLVIAAIG description Helical; Name=1 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 77-103 type TRANSMEM sequence NLFITSLACADLVVGLLVVPFGATLVV description Helical; Name=2 source Swiss-Prot : SWS_FT_FI3 25) chain B residue 116-137 type TRANSMEM sequence LWTSLDVLCVTASIETLCVIAI description Helical; Name=3 source Swiss-Prot : SWS_FT_FI5 26) chain B residue 156-179 type TRANSMEM sequence ARAKVIICTVWAISALVSFLPIMM description Helical; Name=4 source Swiss-Prot : SWS_FT_FI6 27) chain B residue 206-231 type TRANSMEM sequence AYAIASSIISFYIPLLIMIFVALRVY description Helical; Name=5 source Swiss-Prot : SWS_FT_FI7 28) chain B residue 286-315 type TRANSMEM sequence HKALKTLGIIMGVFTLCWLPFFLVNIVNVF description Helical; Name=6 source Swiss-Prot : SWS_FT_FI8 29) chain B residue 321-343 type TRANSMEM sequence PDWLFVAFNWLGYANSAMNPIIY description Helical; Name=7 source Swiss-Prot : SWS_FT_FI9 30) chain B residue 121 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18594507, ECO:0007744|PDB:2VT4 source Swiss-Prot : SWS_FT_FI10 31) chain B residue 211 type BINDING sequence S description BINDING => ECO:0000269|PubMed:18594507, ECO:0007744|PDB:2VT4 source Swiss-Prot : SWS_FT_FI10 32) chain B residue 329 type BINDING sequence N description BINDING => ECO:0000269|PubMed:18594507, ECO:0007744|PDB:2VT4 source Swiss-Prot : SWS_FT_FI10 33) chain B residue 358 type LIPID sequence A description S-palmitoyl cysteine => ECO:0000250 source Swiss-Prot : SWS_FT_FI11 34) chain B residue 68-76 type TOPO_DOM sequence STQRLQTLT description Cytoplasmic => ECO:0000269|PubMed:18594507 source Swiss-Prot : SWS_FT_FI2 35) chain B residue 138-155 type TOPO_DOM sequence DRYLAITSPFRYQSLMTR description Cytoplasmic => ECO:0000269|PubMed:18594507 source Swiss-Prot : SWS_FT_FI2 36) chain B residue 232-315 type TOPO_DOM sequence REAKEQIRKIDRASKRKRVMLMREHKALKTLGIIMGVFTL CWLPFFLVNIVNVF description Cytoplasmic => ECO:0000269|PubMed:18594507 source Swiss-Prot : SWS_FT_FI2

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