eF-site ID 2y8i-X PDB Code 2y8i Chain X click to enlarge Title Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 Classification MOTOR PROTEIN Compound MYOSIN-2 HEAVY CHAIN Source (MYS2_DICDI) Sequence X:  NPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDP KERDSYECGEIVSETSDSFTFKTVDGQDRQVKKDDANQRN PIKFDGVEDMSELSYLNEPAVFHNLRVRYNQDLIYTYSGL FLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDV AYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAG RNQANGSGVLEQQILQANPILEAFGNAKTTRNNNSSRFGK FIEIQFNSAGFISGASIQSYLLEKSRVVFQSETERNYHIF YQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKGVSDS EEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEK GAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAG RDLVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVL CQERKAYFIGVLDISGFEIFKVNSFEQLCINYTNEKLQQF FNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDLIDGRQ PPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEP RFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFK DSSDNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASL MATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNAV LEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAEDSQK ATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEARE Description Functional site 1) chain X residue 127 type sequence N description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 2) chain X residue 128 type sequence P description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 3) chain X residue 130 type sequence K description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 4) chain X residue 135 type sequence Y description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 5) chain X residue 182 type sequence G description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 6) chain X residue 184 type sequence G description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 7) chain X residue 185 type sequence K description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 8) chain X residue 186 type sequence T description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 9) chain X residue 187 type sequence E description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 10) chain X residue 233 type sequence N description BINDING SITE FOR RESIDUE ADP X 1001 source : AC1 11) chain X residue 186 type sequence T description BINDING SITE FOR RESIDUE MG X 1002 source : AC2 12) chain X residue 237 type sequence S description BINDING SITE FOR RESIDUE MG X 1002 source : AC2 13) chain X residue 454 type sequence D description BINDING SITE FOR RESIDUE MG X 1002 source : AC2 14) chain X residue 181 type catalytic sequence S description 534 source MCSA : MCSA1 15) chain X residue 182 type catalytic sequence G description 534 source MCSA : MCSA1 16) chain X residue 186 type catalytic sequence T description 534 source MCSA : MCSA1 17) chain X residue 233 type catalytic sequence N description 534 source MCSA : MCSA1 18) chain X residue 236 type catalytic sequence S description 534 source MCSA : MCSA1 19) chain X residue 237 type catalytic sequence S description 534 source MCSA : MCSA1 20) chain X residue 457 type catalytic sequence G description 534 source MCSA : MCSA1 21) chain X residue 459 type catalytic sequence E description 534 source MCSA : MCSA1 22) chain X residue 130 type MOD_RES sequence K description N6,N6-dimethyllysine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 23) chain X residue 179 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI1

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