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eF-site ID
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2y82-B |
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PDB Code
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2y82 |
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Chain
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B |
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click to enlarge
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Title
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Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs |
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Classification
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BLOOD CLOTTING |
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Compound
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ACTIVATED FACTOR XA HEAVY CHAIN |
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Source
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ORGANISM_COMMON: HUMAN; ORGANISM_SCIENTIFIC: HOMO SAPIENS; |
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Sequence
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B: |
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACI
PTGPYPCGKQTLE
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Description
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(1) |
ACTIVATED FACTOR XA HEAVY CHAIN (E.C.3.4.21.6), FACTOR X LIGHT CHAIN (E.C.3.4.21.6)
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Functional site
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1)
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chain |
B |
| residue |
21-36 |
| type |
prosite |
| sequence |
CSCARGYTLADNGKAC
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| description |
EGF_2 EGF-like domain signature 2. CtCleGFegkn....C
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| source |
prosite : PS01186
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