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eF-site ID
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2y7c-B |
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PDB Code
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2y7c |
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Chain
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B |
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click to enlarge
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Title
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Atomic model of the Ocr-bound methylase complex from the Type I restriction-modification enzyme EcoKI (M2S1). Based on fitting into EM map 1534. |
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Classification
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TRANSFERASE |
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Compound
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TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN |
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Source
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ORGANISM_SCIENTIFIC: ESCHERICHIA COLI; |
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Sequence
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B: |
MNNNDLVAKLWKLCDNLRDGGVSYQNYVNELASLLFLKMC
KETGQEAEYLPEGYRWDDLKSRIGQEQLQFYRKMLVHLGE
DDKKLVQAVFHNVSTTITEPKQITALVSNMDSLDWYNGAH
GKSRDDFGDMYEGLLQKNANETKSGAGQYFTPRPLIKTII
HLLKPQPREVVQDPAAGTAGFLIEADRYVKSQTNDLDDLD
GDTQDFQIHRAFIGLELVPGTRRLALMNCLLHDIEGNLDH
GGAIRLGNTLGSDGENLPKAHIVATNPPFGSAAGTNITRT
FVHPTSNKQLCFMQHIIETLHPGGRAAVVVPDNVLFEGGK
GTDIRRDLMDKCHLHTILRLPTGIFYAQGVKTNVLFFTKG
TVANPNQDKNCTDDVWVYDLRTNMPSFGKRTPFTDEHLQP
FERVYGEDPHGLSPRTEGEWSFNAEETEVADSEENKNTDQ
HLATSRWRKFSREWIRTAKSDSLDISWLKDKDSIDADSLP
EPDVLAAEAMGELVQALSELDALMRELGASDEADLQRQLL
EEAFGGVKE
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Description
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(1) |
TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (E.C.3.1.21.3), TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (E.C.3.1.21.3, 2.1.1.72), GENE 0.3 PROTEIN
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Functional site
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1)
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chain |
B |
| residue |
263-269 |
| type |
prosite |
| sequence |
VATNPPF
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| description |
N6_MTASE N-6 Adenine-specific DNA methylases signature. VATNPPF
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| source |
prosite : PS00092
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2)
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chain |
B |
| residue |
148 |
| type |
BINDING |
| sequence |
Q
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| description |
BINDING => ECO:0000250|UniProtKB:Q89Z59
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| source |
Swiss-Prot : SWS_FT_FI1
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3)
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chain |
B |
| residue |
178 |
| type |
BINDING |
| sequence |
T
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| description |
BINDING => ECO:0000250|UniProtKB:Q89Z59
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| source |
Swiss-Prot : SWS_FT_FI1
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4)
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chain |
B |
| residue |
216 |
| type |
BINDING |
| sequence |
E
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| description |
BINDING => ECO:0000250|UniProtKB:Q89Z59
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| source |
Swiss-Prot : SWS_FT_FI1
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