eF-site ID 2y5w-AB PDB Code 2y5w Chain A, B click to enlarge Title Crystal structure of Drosophila melanogaster kinesin-1 motor domain dimer Classification MOTOR PROTEIN Compound KINESIN HEAVY CHAIN Source Drosophila melanogaster (Fruit fly) (KINH_DROME) Sequence A:  EDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIA GKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIF AYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAM EVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRV PYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSS RSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKVKNIN KSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNA RTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEE LTAEEWKRRYEKEK B:  EDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIA GKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIF AYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAM EVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRV PYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSS RSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKNINKS LSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNART TIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELT AEEWKRRYEK Description Functional site 1) chain A residue 18 type sequence R description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 2) chain A residue 20 type sequence R description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 3) chain A residue 21 type sequence P description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 4) chain A residue 94 type sequence T description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 5) chain A residue 95 type sequence S description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 6) chain A residue 96 type sequence S description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 7) chain A residue 97 type sequence G description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 8) chain A residue 98 type sequence K description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 9) chain A residue 99 type sequence T description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 10) chain A residue 100 type sequence H description BINDING SITE FOR RESIDUE ADP A 600 source : AC1 11) chain A residue 99 type sequence T description BINDING SITE FOR RESIDUE MG A 601 source : AC2 12) chain B residue 18 type sequence R description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 13) chain B residue 20 type sequence R description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 14) chain B residue 21 type sequence P description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 15) chain B residue 94 type sequence T description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 16) chain B residue 95 type sequence S description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 17) chain B residue 96 type sequence S description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 18) chain B residue 97 type sequence G description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 19) chain B residue 98 type sequence K description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 20) chain B residue 99 type sequence T description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 21) chain B residue 100 type sequence H description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 22) chain B residue 130 type sequence E description BINDING SITE FOR RESIDUE ADP B 600 source : AC3 23) chain A residue 92 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 92 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 25) chain A residue 232-243 type prosite sequence GKLYLVDLAGSE description KINESIN_MOTOR_1 Kinesin motor domain signature. GKLyLVDLAGSE source prosite : PS00411

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