eF-site ID 2y1n-C PDB Code 2y1n Chain C click to enlarge Title Structure of c-Cbl-ZAP-70 peptide complex Classification LIGASE/TRANSFERASE Compound E3 UBIQUITIN-PROTEIN LIGASE Source Homo sapiens (Human) (ZAP70_HUMAN) Sequence C:  DKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDT YQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTIS LFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPS GLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHE VHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPW SSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSY IFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDG FREGFYLFPDGRNQNPDLTGLCEDHIKVTQEQYELYCEMG STFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQG CPFCRCEIKGTEPIVVDPFD Description Functional site 1) chain C residue 381 type sequence C description BINDING SITE FOR RESIDUE ZN C 1436 source : AC3 2) chain C residue 384 type sequence C description BINDING SITE FOR RESIDUE ZN C 1436 source : AC3 3) chain C residue 401 type sequence C description BINDING SITE FOR RESIDUE ZN C 1436 source : AC3 4) chain C residue 404 type sequence C description BINDING SITE FOR RESIDUE ZN C 1436 source : AC3 5) chain C residue 396 type sequence C description BINDING SITE FOR RESIDUE ZN C 1437 source : AC4 6) chain C residue 398 type sequence H description BINDING SITE FOR RESIDUE ZN C 1437 source : AC4 7) chain C residue 416 type sequence C description BINDING SITE FOR RESIDUE ZN C 1437 source : AC4 8) chain C residue 419 type sequence C description BINDING SITE FOR RESIDUE ZN C 1437 source : AC4 9) chain C residue 229 type sequence D description BINDING SITE FOR RESIDUE CA C 1438 source : AC6 10) chain C residue 231 type sequence T description BINDING SITE FOR RESIDUE CA C 1438 source : AC6 11) chain C residue 233 type sequence N description BINDING SITE FOR RESIDUE CA C 1438 source : AC6 12) chain C residue 235 type sequence Y description BINDING SITE FOR RESIDUE CA C 1438 source : AC6 13) chain C residue 240 type sequence E description BINDING SITE FOR RESIDUE CA C 1438 source : AC6 14) chain C residue 294 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 15) chain C residue 240 type MOD_RES sequence E description Phosphotyrosine => ECO:0000269|PubMed:8943331, ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI2 16) chain C residue 229 type MOD_RES sequence D description Phosphotyrosine => ECO:0000269|PubMed:8943331, ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI2 17) chain C residue 231 type MOD_RES sequence T description Phosphotyrosine => ECO:0000269|PubMed:8943331, ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI2 18) chain C residue 233 type MOD_RES sequence N description Phosphotyrosine => ECO:0000269|PubMed:8943331, ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI2 19) chain C residue 235 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000269|PubMed:8943331, ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI2 20) chain C residue 371 type MOD_RES sequence Y description Phosphotyrosine; by INSR => ECO:0000269|PubMed:11997497 source Swiss-Prot : SWS_FT_FI4

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