|
|
eF-site ID
|
2y1l-E |
|
PDB Code
|
2y1l |
|
Chain
|
E |
|
click to enlarge
|
|
|
Title
|
Caspase-8 in Complex with DARPin-8.4 |
|
Classification
|
HYDROLASE/INHIBITOR |
|
Compound
|
CASPASE-8 |
|
Source
|
Homo sapiens (Human) (2Y1L) |
|
|
Sequence
|
E: |
DLGKKLLEAARAGRDDEVRILMANGADVNAEDASGWTPLH
LAAFNGHLEIVEVLLKNGADVNAVDHAGMTPLRLAALFGH
LEIVEVLLKNGADVNANDMEGHTPLHLAAMFGHLEIVEVL
LKNGADVNAQDKFGKTAFDISIDNGNEDLAEILQKL
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
E |
| residue |
144 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE SO4 B 1480
|
| source |
: AC3
|
|
|
2)
|
chain |
E |
| residue |
19 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE EDO E 1169
|
| source |
: AC6
|
|
|
3)
|
chain |
E |
| residue |
20 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE EDO E 1169
|
| source |
: AC6
|
|
|
4)
|
chain |
E |
| residue |
23 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE EDO E 1169
|
| source |
: AC6
|
|
|
5)
|
chain |
E |
| residue |
44 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE EDO E 1169
|
| source |
: AC6
|
|
|
6)
|
chain |
E |
| residue |
53 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE EDO E 1169
|
| source |
: AC6
|
|
|
|