eF-site ID 2y0r-X PDB Code 2y0r Chain X click to enlarge Title Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 Classification MOTOR PROTEIN Compound MYOSIN-2 HEAVY CHAIN Source (MYS2_DICDI) Sequence X:  NPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDP KERDSYECGEIVSETSDSFTFKTVDGQDRQVKKDDANQRN PIKFDGVEDMSELSYLNEPAVFHNLRVRYNQDLIYTYSGL FLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDV AYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAG RNQANGSGVLEQQILQANPILEAFGNAKTTRNNNSSRFGK FIEIQFNSAGFISGASIQSYLLEKSRVVFQSETERNYHIF YQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKGVSDS EEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEK GAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAG RDLVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVL CQERKAYFIGVLDISGFEIFKVNSFEQLCINYTNEKLQQF FNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDLIDGRQ PPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEP RFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFK DSSDNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASL MATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNAV LEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAEDSQK ATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEARE Description Functional site 1) chain X residue 181 type catalytic sequence S description 534 source MCSA : MCSA1 2) chain X residue 182 type catalytic sequence G description 534 source MCSA : MCSA1 3) chain X residue 186 type catalytic sequence T description 534 source MCSA : MCSA1 4) chain X residue 233 type catalytic sequence N description 534 source MCSA : MCSA1 5) chain X residue 236 type catalytic sequence S description 534 source MCSA : MCSA1 6) chain X residue 237 type catalytic sequence S description 534 source MCSA : MCSA1 7) chain X residue 457 type catalytic sequence G description 534 source MCSA : MCSA1 8) chain X residue 459 type catalytic sequence E description 534 source MCSA : MCSA1 9) chain X residue 179 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI1 10) chain X residue 130 type MOD_RES sequence K description N6,N6-dimethyllysine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2

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