|
|
eF-site ID
|
2y0b-C |
|
PDB Code
|
2y0b |
|
Chain
|
C |
|
click to enlarge
|
|
|
Title
|
Caspase-3 in Complex with an Inhibitory DARPin-3.4_S76R |
|
Classification
|
HYDROLASE/PROTEIN BINDING |
|
Compound
|
CASPASE-3 SUBUNIT P17 |
|
Source
|
(2Y0B) |
|
|
Sequence
|
C: |
DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAAN
LRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSS
FVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTG
KPKLFIIQAXRGTELDCGIET
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
71 |
| type |
|
| sequence |
A
|
| description |
BINDING SITE FOR RESIDUE MRD C 1175
|
| source |
: AC3
|
|
|
2)
|
chain |
C |
| residue |
87 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE MRD C 1175
|
| source |
: AC3
|
|
|
3)
|
chain |
C |
| residue |
89 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE MRD C 1175
|
| source |
: AC3
|
|
|
4)
|
chain |
C |
| residue |
121 |
| type |
MOD_RES |
| sequence |
H
|
| description |
(Microbial infection) ADP-riboxanated arginine => ECO:0000269|PubMed:35338844, ECO:0000269|PubMed:35446120, ECO:0000269|PubMed:36423631
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
C |
| residue |
163 |
| type |
MOD_RES |
| sequence |
X
|
| description |
(Microbial infection) ADP-riboxanated arginine => ECO:0000269|PubMed:35338844, ECO:0000269|PubMed:35446120, ECO:0000269|PubMed:36423631
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
C |
| residue |
163 |
| type |
MOD_RES |
| sequence |
X
|
| description |
S-nitrosocysteine; in inhibited form => ECO:0000269|PubMed:10213689
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
C |
| residue |
62 |
| type |
catalytic |
| sequence |
T
|
| description |
815
|
| source |
MCSA : MCSA2
|
|
|
8)
|
chain |
C |
| residue |
63 |
| type |
catalytic |
| sequence |
S
|
| description |
815
|
| source |
MCSA : MCSA2
|
|
|
9)
|
chain |
C |
| residue |
121 |
| type |
catalytic |
| sequence |
H
|
| description |
815
|
| source |
MCSA : MCSA2
|
|
|
10)
|
chain |
C |
| residue |
122 |
| type |
catalytic |
| sequence |
G
|
| description |
815
|
| source |
MCSA : MCSA2
|
|
|
11)
|
chain |
C |
| residue |
163 |
| type |
catalytic |
| sequence |
X
|
| description |
815
|
| source |
MCSA : MCSA2
|
|
|
|