eF-site ID 2xxz-B PDB Code 2xxz Chain B click to enlarge Title Crystal structure of the human JMJD3 jumonji domain Classification OXIDOREDUCTASE Compound LYSINE-SPECIFIC DEMETHYLASE 6B Source Homo sapiens (Human) (KDM6B_HUMAN) Sequence B:  REKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRG LAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENW DLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQHHII KFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTILGMNTV QLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEH YWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQ RPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLA LERYEW Description Functional site 1) chain B residue 1387 type sequence H description BINDING SITE FOR RESIDUE NI B 2500 source : AC3 2) chain B residue 1389 type sequence E description BINDING SITE FOR RESIDUE NI B 2500 source : AC3 3) chain B residue 1188 type sequence E description BINDING SITE FOR RESIDUE NA A 2495 source : AC4 4) chain B residue 1200 type sequence Q description BINDING SITE FOR RESIDUE EDO A 2496 source : AC5 5) chain B residue 1183 type sequence P description BINDING SITE FOR RESIDUE EDO A 2497 source : AC6 6) chain B residue 1184 type sequence S description BINDING SITE FOR RESIDUE EDO A 2497 source : AC6 7) chain B residue 1201 type sequence F description BINDING SITE FOR RESIDUE EDO A 2497 source : AC6 8) chain B residue 1190 type sequence K description BINDING SITE FOR RESIDUE EDO B 2501 source : AC8 9) chain B residue 1191 type sequence R description BINDING SITE FOR RESIDUE EDO B 2501 source : AC8 10) chain B residue 1497 type sequence Y description BINDING SITE FOR RESIDUE EDO B 2501 source : AC8 11) chain B residue 1376 type sequence Y description BINDING SITE FOR RESIDUE 8XQ B 3001 source : BC2 12) chain B residue 1378 type sequence K description BINDING SITE FOR RESIDUE 8XQ B 3001 source : BC2 13) chain B residue 1384 type sequence T description BINDING SITE FOR RESIDUE 8XQ B 3001 source : BC2 14) chain B residue 1387 type sequence H description BINDING SITE FOR RESIDUE 8XQ B 3001 source : BC2 15) chain B residue 1389 type sequence E description BINDING SITE FOR RESIDUE 8XQ B 3001 source : BC2 16) chain B residue 1397 type sequence N description BINDING SITE FOR RESIDUE 8XQ B 3001 source : BC2 17) chain B residue 1407 type sequence W description BINDING SITE FOR RESIDUE 8XQ B 3001 source : BC2 18) chain B residue 1467 type sequence H description BINDING SITE FOR RESIDUE 8XQ B 3001 source : BC2 19) chain B residue 1390 type BINDING sequence N description BINDING => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 1392 type BINDING sequence N description BINDING => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 21) chain B residue 1470 type BINDING sequence Q description BINDING => ECO:0000250|UniProtKB:O14607 source Swiss-Prot : SWS_FT_FI2

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