eF-site ID 2xxz-A PDB Code 2xxz Chain A click to enlarge Title Crystal structure of the human JMJD3 jumonji domain Classification OXIDOREDUCTASE Compound LYSINE-SPECIFIC DEMETHYLASE 6B Source Homo sapiens (Human) (KDM6B_HUMAN) Sequence A:  REKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRG LAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENW DLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEHH IIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLS HVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIG PGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDL YASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWN VGPLTAYQYQLA Description (1)  LYSINE-SPECIFIC DEMETHYLASE 6B (E.C.1.14.11.-) Functional site 1) chain A residue 1387 type sequence H description BINDING SITE FOR RESIDUE NI A 2494 source : AC1 2) chain A residue 1389 type sequence E description BINDING SITE FOR RESIDUE NI A 2494 source : AC1 3) chain A residue 1287 type sequence E description BINDING SITE FOR RESIDUE NA A 2495 source : AC4 4) chain A residue 1185 type sequence I description BINDING SITE FOR RESIDUE EDO A 2496 source : AC5 5) chain A residue 1186 type sequence Y description BINDING SITE FOR RESIDUE EDO A 2496 source : AC5 6) chain A residue 1204 type sequence D description BINDING SITE FOR RESIDUE EDO A 2497 source : AC6 7) chain A residue 1489 type sequence Q description BINDING SITE FOR RESIDUE EDO A 2497 source : AC6 8) chain A residue 1330 type sequence D description BINDING SITE FOR RESIDUE EDO A 2498 source : AC7 9) chain A residue 1370 type sequence M description BINDING SITE FOR RESIDUE EDO A 2498 source : AC7 10) chain A residue 1191 type sequence R description BINDING SITE FOR RESIDUE EDO B 2501 source : AC8 11) chain A residue 1227 type sequence S description BINDING SITE FOR RESIDUE EDO A 2499 source : AC9 12) chain A residue 1228 type sequence T description BINDING SITE FOR RESIDUE EDO A 2499 source : AC9 13) chain A residue 1401 type sequence G description BINDING SITE FOR RESIDUE EDO A 2499 source : AC9 14) chain A residue 1476 type sequence N description BINDING SITE FOR RESIDUE EDO A 2499 source : AC9 15) chain A residue 1376 type sequence Y description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 16) chain A residue 1378 type sequence K description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 17) chain A residue 1384 type sequence T description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 18) chain A residue 1387 type sequence H description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 19) chain A residue 1389 type sequence E description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 20) chain A residue 1397 type sequence N description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 21) chain A residue 1407 type sequence W description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 22) chain A residue 1461 type sequence I description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 23) chain A residue 1467 type sequence H description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 24) chain A residue 1477 type sequence N description BINDING SITE FOR RESIDUE 8XQ A 3001 source : BC1 25) chain A residue 1470 type BINDING sequence Q description BINDING => ECO:0000250|UniProtKB:O14607 source Swiss-Prot : SWS_FT_FI2 26) chain A residue 1390 type BINDING sequence N description BINDING => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 27) chain A residue 1392 type BINDING sequence N description BINDING => ECO:0000305 source Swiss-Prot : SWS_FT_FI1

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