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eF-site ID
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2xwj-E |
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PDB Code
|
2xwj |
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Chain
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E |
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click to enlarge
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Title
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Crystal Structure of Complement C3b in Complex with Factor B |
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Classification
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HYDROLASE |
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Compound
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COMPLEMENT C3 BETA CHAIN |
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Source
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ORGANISM_COMMON: HUMAN; ORGANISM_SCIENTIFIC: HOMO SAPIENS; |
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Sequence
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E: |
SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDF
PGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKKGRNK
FVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPGST
VLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQN
QLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEV
KEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKK
VEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSR
KVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERS
GIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPA
YRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITV
RTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTE
LRPGETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAG
RQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQR
EVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLK
IEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKAD
IGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQ
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Description
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Functional site
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1)
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chain |
E |
| residue |
16 |
| type |
CARBOHYD |
| sequence |
S
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17310251, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6546754
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| source |
Swiss-Prot : SWS_FT_FI2
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|
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2)
|
chain |
E |
| residue |
48 |
| type |
CARBOHYD |
| sequence |
S
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17310251, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6546754
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
E |
| residue |
275 |
| type |
CARBOHYD |
| sequence |
S
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17310251, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6546754
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
E |
| residue |
281 |
| type |
CARBOHYD |
| sequence |
S
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17310251, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6546754
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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