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eF-site ID
|
2xq4-A |
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PDB Code
|
2xq4 |
|
Chain
|
A |
|
click to enlarge
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Title
|
Pentameric ligand gated ion channel GLIC in complex with tetramethylarsonium (TMAs) |
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Classification
|
MEMBRANE PROTEIN |
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Compound
|
GLR4197 PROTEIN |
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Source
|
(Q7NDN8_GLOVI) |
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Sequence
|
A: |
PPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSW
KDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDA
DVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLH
IYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTA
VVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLF
ILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLP
KTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPAR
AASITRASRIAFPVVFLLANIILAFLFFGF
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Description
|
(1) |
GLR4197 PROTEIN
|
|
Functional site
|
|
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1)
|
chain |
A |
| residue |
193-215 |
| type |
TRANSMEM |
| sequence |
YFSYIPNIILPMLFILFISWTAF
|
| description |
Helical
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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2)
|
chain |
A |
| residue |
219-243 |
| type |
TRANSMEM |
| sequence |
SYEANVTLVVSTLIAHIAFNILVET
|
| description |
Helical
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
A |
| residue |
252-280 |
| type |
TRANSMEM |
| sequence |
TYTGAIIFMIYLFYFVAVIEVTVQHYLKV
|
| description |
Helical
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
284-316 |
| type |
TRANSMEM |
| sequence |
PARAASITRASRIAFPVVFLLANIILAFLFFGF
|
| description |
Helical
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
244-251 |
| type |
TOPO_DOM |
| sequence |
NLPKTPYM
|
| description |
Periplasmic => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
216-218 |
| type |
TOPO_DOM |
| sequence |
WST
|
| description |
Cytoplasmic => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
A |
| residue |
281-283 |
| type |
TOPO_DOM |
| sequence |
ESQ
|
| description |
Cytoplasmic => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|