eF-site ID 2xms-A PDB Code 2xms Chain A click to enlarge Title Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor Classification SIGNALING PROTEIN Compound PROTEIN NDRG2 Source Homo sapiens (Human) (NDRG2_HUMAN) Sequence A:  AKTHSVETPYGSVTFTVYGTPYPYRPAILTYHDVGLNYKS CFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQ YPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYAL NHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMI LGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSY NNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSK LDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYM A Description Functional site 1) chain A residue 83 type sequence R description BINDING SITE FOR RESIDUE CL A 1305 source : AC1 2) chain A residue 85 type sequence H description BINDING SITE FOR RESIDUE CL A 1305 source : AC1 3) chain A residue 61 type sequence Y description BINDING SITE FOR RESIDUE IMD A 1306 source : AC2 4) chain A residue 62 type sequence K description BINDING SITE FOR RESIDUE IMD A 1306 source : AC2 5) chain A residue 66 type sequence Q description BINDING SITE FOR RESIDUE IMD A 1306 source : AC2 6) chain A residue 85 type sequence H description BINDING SITE FOR RESIDUE IMD A 1306 source : AC2 7) chain A residue 60 type sequence N description BINDING SITE FOR RESIDUE IMD A 1307 source : AC3 8) chain A residue 61 type sequence Y description BINDING SITE FOR RESIDUE IMD A 1307 source : AC3 9) chain A residue 87 type sequence D description BINDING SITE FOR RESIDUE IMD A 1307 source : AC3 10) chain A residue 91 type sequence M description BINDING SITE FOR RESIDUE IMD A 1307 source : AC3 11) chain A residue 92 type sequence E description BINDING SITE FOR RESIDUE IMD A 1307 source : AC3 12) chain A residue 93 type sequence E description BINDING SITE FOR RESIDUE IMD A 1307 source : AC3

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