eF-site ID 2xmr-A PDB Code 2xmr Chain A click to enlarge Title Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor Classification SIGNALING PROTEIN Compound PROTEIN NDRG2 Source Homo sapiens (Human) (NDRG2_HUMAN) Sequence A:  AKTHSVETPYGSVTFTVYGTPAPARPAILTYHDVGLNYKS CFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQ YPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYAL NHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMI LGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSY NNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSK LDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYM A Description Functional site 1) chain A residue 47 type sequence A description BINDING SITE FOR RESIDUE CA A 1305 source : AC1 2) chain A residue 302 type sequence Y description BINDING SITE FOR RESIDUE CA A 1305 source : AC1 3) chain A residue 61 type sequence Y description BINDING SITE FOR RESIDUE ACT A 1306 source : AC4 4) chain A residue 75 type sequence Q description BINDING SITE FOR RESIDUE ACT A 1306 source : AC4 5) chain A residue 78 type sequence I description BINDING SITE FOR RESIDUE ACT A 1306 source : AC4 6) chain A residue 83 type sequence R description BINDING SITE FOR RESIDUE ACT A 1306 source : AC4 7) chain A residue 85 type sequence H description BINDING SITE FOR RESIDUE ACT A 1306 source : AC4 8) chain A residue 58 type sequence G description BINDING SITE FOR RESIDUE GOL A 1307 source : AC7 9) chain A residue 59 type sequence L description BINDING SITE FOR RESIDUE GOL A 1307 source : AC7 10) chain A residue 60 type sequence N description BINDING SITE FOR RESIDUE GOL A 1307 source : AC7 11) chain A residue 63 type sequence S description BINDING SITE FOR RESIDUE GOL A 1307 source : AC7 12) chain A residue 91 type sequence M description BINDING SITE FOR RESIDUE GOL A 1307 source : AC7 13) chain A residue 206 type sequence I description BINDING SITE FOR RESIDUE GOL A 1307 source : AC7 14) chain A residue 210 type sequence A description BINDING SITE FOR RESIDUE GOL A 1307 source : AC7 15) chain A residue 212 type sequence N description BINDING SITE FOR RESIDUE GOL A 1307 source : AC7

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