eF-site ID 2xk5-B PDB Code 2xk5 Chain B click to enlarge Title Crystal structure of K6-linked diubiquitin Classification PROTEIN BINDING Compound UBIQUITIN Source (UBIQ_HUMAN) Sequence B:  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPQQ QRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG Description Functional site 1) chain B residue 18 type sequence E description BINDING SITE FOR RESIDUE ZN B 1076 source : AC3 2) chain B residue 18 type sequence E description BINDING SITE FOR RESIDUE ZN B 1076 source : AC3 3) chain B residue 21 type sequence D description BINDING SITE FOR RESIDUE ZN B 1076 source : AC3 4) chain B residue 29 type sequence K description BINDING SITE FOR RESIDUE ZN B 1076 source : AC3 5) chain B residue 1 type sequence M description BINDING SITE FOR RESIDUE ZN B 1077 source : AC5 6) chain B residue 16 type sequence E description BINDING SITE FOR RESIDUE ZN B 1077 source : AC5 7) chain B residue 32 type sequence D description BINDING SITE FOR RESIDUE ZN B 1077 source : AC5 8) chain B residue 58 type sequence D description BINDING SITE FOR RESIDUE ZN B 1078 source : AC7 9) chain B residue 54 type SITE sequence R description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 10) chain B residue 72 type SITE sequence R description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 11) chain B residue 68 type SITE sequence H description Essential for function source Swiss-Prot : SWS_FT_FI2 12) chain B residue 65 type MOD_RES sequence S description Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291 source Swiss-Prot : SWS_FT_FI3 13) chain B residue 63 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106 source Swiss-Prot : SWS_FT_FI12 14) chain B residue 29 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127 source Swiss-Prot : SWS_FT_FI10 15) chain B residue 66 type MOD_RES sequence T description (Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457 source Swiss-Prot : SWS_FT_FI4 16) chain B residue 6 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603 source Swiss-Prot : SWS_FT_FI6 17) chain B residue 48 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144 source Swiss-Prot : SWS_FT_FI8 18) chain B residue 11 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144 source Swiss-Prot : SWS_FT_FI8 19) chain B residue 33 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577 source Swiss-Prot : SWS_FT_FI11 20) chain B residue 27 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860 source Swiss-Prot : SWS_FT_FI9 21) chain B residue 27-52 type prosite sequence KAKIQDKEGIPPQQQRLIFAGKQLED description UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD source prosite : PS00299

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