|
|
eF-site ID
|
2xcf-B |
|
PDB Code
|
2xcf |
|
Chain
|
B |
|
click to enlarge
|
|
|
Title
|
Crystal structure of HCV NS3 protease with a boronate inhibitor |
|
Classification
|
HYDROLASE |
|
Compound
|
NS3 PROTEASE |
|
Source
|
(C9WU77_9HEPC) |
|
|
Sequence
|
B: |
QVEGEVQIVSTATQTFLATCINGVCWTVYHGAGTRTIASP
KGPVIQMYTNVDQDLVGWPAPQGSRSLTPCTCGSSDLYLV
TRHADVIPVRRRGDSRGSLLSPRPISYLKGSAGGPLLCPA
GHAVGLFRAAVCTRGVAKAVDFIPVENLETTMR
|
|
|
Description
|
(1) |
NS3 PROTEASE, NS4A
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
97 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN B 400
|
| source |
: AC4
|
|
|
2)
|
chain |
B |
| residue |
99 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN B 400
|
| source |
: AC4
|
|
|
3)
|
chain |
B |
| residue |
145 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN B 400
|
| source |
: AC4
|
|
|
|