eF-site ID 2xbu-B PDB Code 2xbu Chain B click to enlarge Title Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with GMP (monoclinic crystal form) Classification TRANSFERASE Compound HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE Source (HPRT_YEAST) Sequence B:  DKQYISYNNVHQLCQVSAERIKNFKPDLIIAIGGGGFIPA RILRTFLKEPGVPTIRIFAIILSLYEDLVKVSRTQWIDYE QCKLDLVGKNVLIVDEVDDTRTTLHYALSELEKDAAEQAK AKGIDTEKSPEMKTNFGIFVLHDKQKPKKADLPAEMLNDK NRYFAAKTVPDKWYAYPWESTDIVFHTRMAIEQGNDIFIP EQE Description Functional site 1) chain B residue 36 type sequence I description BINDING SITE FOR RESIDUE MG B 301 source : AC3 2) chain B residue 40 type sequence G description BINDING SITE FOR RESIDUE MG B 301 source : AC3 3) chain B residue 110 type sequence D description BINDING SITE FOR RESIDUE MG B 301 source : AC3 4) chain B residue 111 type sequence E description BINDING SITE FOR RESIDUE MG B 301 source : AC3 5) chain B residue 60 type sequence R description BINDING SITE FOR RESIDUE ACT B 1219 source : AC4 6) chain B residue 104 type sequence K description BINDING SITE FOR RESIDUE ACT B 1219 source : AC4 7) chain B residue 114 type sequence D description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 8) chain B residue 115 type sequence T description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 9) chain B residue 116 type sequence R description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 10) chain B residue 117 type sequence T description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 11) chain B residue 118 type sequence T description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 12) chain B residue 159 type sequence K description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 13) chain B residue 188 type sequence W description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 14) chain B residue 189 type sequence Y description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 15) chain B residue 191 type sequence Y description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 16) chain B residue 194 type sequence E description BINDING SITE FOR RESIDUE 5GP B 1220 source : AC5 17) chain B residue 114 type ACT_SITE sequence D description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 85 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 19) chain B residue 110 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 20) chain B residue 159 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 21) chain B residue 188 type BINDING sequence W description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2

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