eF-site ID 2x7l-ABCDEFGHIJKLMNOPQR PDB Code 2x7l Chain A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R click to enlarge Title Implications of the HIV-1 Rev dimer structure at 3.2A resolution for multimeric binding to the Rev response element Classification IMMUNE SYSTEM Compound FAB HEAVY CHAIN Source (REV_HV1B1) Sequence A:  QEQLVESGGRLVTPGTALTLTCKVSGFSLSGFWLNWVRQA PGKGLEWVGAIYRGSGSEWYASWAKGRFTISDTSTTVTLK LTSPTTEDTATYFCAADTTDNGYFTIWGPGTLVTVSSAST KGPSVFPLAPSAKSTSGGTAALGCLVKDYFPEPVTVSWNS GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC NVNHKPSNTKVDKKAEPKSCD B:  ELVMTQTPSSVSEPVGGTVTIKCQASQSISSWLSWYQQKP GQPPKLLIYDASNLASGVPSRFMGSGSGTEYTLTISGVQR EDAATYYCLGGYPAASYRTAFGGGTELEIIRTVAAPSVFI FPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSG NSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVT HQGLSSPVTKSFNRGEC C:  QEQLVESGGRLVTPGTALTLTCKVSGFSLSGFWLNWVRQA PGKGLEWVGAIYRGSGSEWYASWAKGRFTISDTSTTVTLK LTSPTTEDTATYFCAADTTDNGYFTIWGPGTLVTVSSAST KGPSVFPLAPSAKSTSGGTAALGCLVKDYFPEPVTVSWNS GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC NVNHKPSNTKVDKKAEPKSCD D:  ELVMTQTPSSVSEPVGGTVTIKCQASQSISSWLSWYQQKP GQPPKLLIYDASNLASGVPSRFMGSGSGTEYTLTISGVQR EDAATYYCLGGYPAASYRTAFGGGTELEIIRTVAAPSVFI FPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSG NSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVT HQGLSSPVTKSFNRGEC E:  QEQLVESGGRLVTPGTALTLTCKVSGFSLSGFWLNWVRQA PGKGLEWVGAIYRGSGSEWYASWAKGRFTISDTSTTVTLK LTSPTTEDTATYFCAADTTDNGYFTIWGPGTLVTVSSAST KGPSVFPLAPSAKSTSGGTAALGCLVKDYFPEPVTVSWNS GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC NVNHKPSNTKVDKKAEPKSCD F:  ELVMTQTPSSVSEPVGGTVTIKCQASQSISSWLSWYQQKP GQPPKLLIYDASNLASGVPSRFMGSGSGTEYTLTISGVQR EDAATYYCLGGYPAASYRTAFGGGTELEIIRTVAAPSVFI FPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSG NSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVT HQGLSSPVTKSFNRGEC G:  QEQLVESGGRLVTPGTALTLTCKVSGFSLSGFWLNWVRQA PGKGLEWVGAIYRGSGSEWYASWAKGRFTISDTSTTVTLK LTSPTTEDTATYFCAADTTDNGYFTIWGPGTLVTVSSAST KGPSVFPLAPSAKSTSGGTAALGCLVKDYFPEPVTVSWNS GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC NVNHKPSNTKVDKKAEPKSCD H:  QEQLVESGGRLVTPGTALTLTCKVSGFSLSGFWLNWVRQA PGKGLEWVGAIYRGSGSEWYASWAKGRFTISDTSTTVTLK LTSPTTEDTATYFCAADTTDNGYFTIWGPGTLVTVSSAST KGPSVFPLAPSAKSTSGGTAALGCLVKDYFPEPVTVSWNS GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC NVNHKPSNTKVDKKAEPKSCD I:  ELVMTQTPSSVSEPVGGTVTIKCQASQSISSWLSWYQQKP GQPPKLLIYDASNLASGVPSRFMGSGSGTEYTLTISGVQR EDAATYYCLGGYPAASYRTAFGGGTELEIIRTVAAPSVFI FPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSG NSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVT HQGLSSPVTKSFNRGEC J:  QEQLVESGGRLVTPGTALTLTCKVSGFSLSGFWLNWVRQA PGKGLEWVGAIYRGSGSEWYASWAKGRFTISDTSTTVTLK LTSPTTEDTATYFCAADTTDNGYFTIWGPGTLVTVSSAST KGPSVFPLAPSAKSTSGGTAALGCLVKDYFPEPVTVSWNS GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC NVNHKPSNTKVDKKAEPKSCD K:  ELVMTQTPSSVSEPVGGTVTIKCQASQSISSWLSWYQQKP GQPPKLLIYDASNLASGVPSRFMGSGSGTEYTLTISGVQR EDAATYYCLGGYPAASYRTAFGGGTELEIIRTVAAPSVFI FPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSG NSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVT HQGLSSPVTKSFNRGEC L:  ELVMTQTPSSVSEPVGGTVTIKCQASQSISSWLSWYQQKP GQPPKLLIYDASNLASGVPSRFMGSGSGTEYTLTISGVQR EDAATYYCLGGYPAASYRTAFGGGTELEIIRTVAAPSVFI FPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSG NSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVT HQGLSSPVTKSFNRGEC M:  DEDLLKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRER QRQIHSISERILSTYLG N:  DEDLLKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRER QRQIHSISERILSTYLG O:  DEDLLKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRER QRQIHSISERILSTYLG P:  DEDLLKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRER QRQIHSISERILSTYLG Q:  DEDLLKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRER QRQIHSISERILSTYLG R:  DEDLLKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRER QRQIHSISERILSTYLG Description Functional site 1) chain B residue 195-201 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290 2) chain A residue 198-204 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290

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