eF-site ID 2x2r-C PDB Code 2x2r Chain C click to enlarge Title Crystal structure of human kinesin Eg5 in complex with (R)-2-amino-3-((4-chlorophenyl)diphenylmethylthio)propanoic acid Classification CELL CYCLE Compound KINESIN-LIKE PROTEIN KIF11 Source Homo sapiens (Human) (KIF11_HUMAN) Sequence C:  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL ADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGY NCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP RTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSD VSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKG AAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVK IGKLNLVDLAGSENNQSLLTLGRVITALVERTPHVPYRES KLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAH RAKNILNKP Description Functional site 1) chain C residue 24 type sequence R description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 2) chain C residue 26 type sequence R description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 3) chain C residue 27 type sequence P description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 4) chain C residue 107 type sequence T description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 5) chain C residue 108 type sequence G description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 6) chain C residue 109 type sequence T description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 7) chain C residue 110 type sequence G description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 8) chain C residue 111 type sequence K description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 9) chain C residue 112 type sequence T description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 10) chain C residue 113 type sequence F description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 11) chain C residue 118 type sequence E description BINDING SITE FOR RESIDUE ADP C 1366 source : AC7 12) chain C residue 112 type sequence T description BINDING SITE FOR RESIDUE MG C 1368 source : AC8 13) chain C residue 112 type sequence T description BINDING SITE FOR RESIDUE X2O C 1367 source : AC9 14) chain C residue 116 type sequence E description BINDING SITE FOR RESIDUE X2O C 1367 source : AC9 15) chain C residue 117 type sequence G description BINDING SITE FOR RESIDUE X2O C 1367 source : AC9 16) chain C residue 118 type sequence E description BINDING SITE FOR RESIDUE X2O C 1367 source : AC9 17) chain C residue 137 type sequence P description BINDING SITE FOR RESIDUE X2O C 1367 source : AC9 18) chain C residue 211 type sequence Y description BINDING SITE FOR RESIDUE X2O C 1367 source : AC9 19) chain C residue 214 type sequence L description BINDING SITE FOR RESIDUE X2O C 1367 source : AC9 20) chain C residue 221 type sequence R description BINDING SITE FOR RESIDUE X2O C 1367 source : AC9 21) chain C residue 105 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 22) chain C residue 146 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links