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eF-site ID
|
2x2g-A |
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PDB Code
|
2x2g |
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Chain
|
A |
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click to enlarge
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Title
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CRYSTALLOGRAPHIC BINDING STUDIES WITH AN ENGINEERED MONOMERIC VARIANT OF TRIOSEPHOSPHATE ISOMERASE |
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Classification
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ISOMERASE |
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Compound
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TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL |
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Source
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Trypanosoma brucei brucei (TPIS_TRYBB) |
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Sequence
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A: |
SKPQPIAAANWDSLSELIDLFNSTSINHDVQCVVASTFVH
LAMTKERLSHPKFVIAAQNAGNADALASLKDFGVNWIVLG
HSERRWYYGETNEIVADKVAAAVASGFMVIACIGETLQER
ESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGT
GKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSV
NGKNARTLYQQRDVNGFLAGLKPEFVDIIKATQ
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Description
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Functional site
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|
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1)
|
chain |
A |
| residue |
165-175 |
| type |
prosite |
| sequence |
AYEPVWAIGTG
|
| description |
TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG
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| source |
prosite : PS00171
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|
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2)
|
chain |
A |
| residue |
103 |
| type |
ACT_SITE |
| sequence |
G
|
| description |
Electrophile
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| source |
Swiss-Prot : SWS_FT_FI1
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|
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3)
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chain |
A |
| residue |
175 |
| type |
ACT_SITE |
| sequence |
G
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
|
chain |
A |
| residue |
11 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
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