eF-site ID 2x1u-B PDB Code 2x1u Chain B click to enlarge Title Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase Classification ISOMERASE Compound TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL Source null (TPIS_TRYBB) Sequence B:  SKPQPIAAANWKSGSPDSLSELIDLFNSTSINHDVQCVVA STFVHLAMTKERLSHPKFVIAAQNAGNADALASLKDFGVN WIVLGHSERRWYYGETNEIVADKVAAAVASGFMVIACIGE TLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPV WAIGTGKVATPQQAQEAHALIRSWVSSKIGADVAGELRIL YGGSVNGKNARTLYQQRDVNGFLAGLKPEFVDIIKATQ Description Functional site 1) chain B residue 171 type sequence A description BINDING SITE FOR RESIDUE SO4 B 1251 source : AC4 2) chain B residue 173 type sequence G description BINDING SITE FOR RESIDUE SO4 B 1251 source : AC4 3) chain B residue 213 type sequence S description BINDING SITE FOR RESIDUE SO4 B 1251 source : AC4 4) chain B residue 233 type sequence A description BINDING SITE FOR RESIDUE SO4 B 1251 source : AC4 5) chain B residue 234 type sequence G description BINDING SITE FOR RESIDUE SO4 B 1251 source : AC4 6) chain B residue 32 type sequence S description BINDING SITE FOR RESIDUE SO4 B 1252 source : AC5 7) chain B residue 33 type sequence I description BINDING SITE FOR RESIDUE SO4 B 1252 source : AC5 8) chain B residue 34 type sequence N description BINDING SITE FOR RESIDUE SO4 B 1252 source : AC5 9) chain B residue 35 type sequence H description BINDING SITE FOR RESIDUE SO4 B 1252 source : AC5 10) chain B residue 247 type sequence K description BINDING SITE FOR RESIDUE SO4 B 1252 source : AC5 11) chain B residue 250 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 1252 source : AC5 12) chain B residue 155 type sequence K description BINDING SITE FOR RESIDUE SO4 B 1253 source : AC6 13) chain B residue 156 type sequence K description BINDING SITE FOR RESIDUE SO4 B 1253 source : AC6 14) chain B residue 103 type ACT_SITE sequence G description Electrophile source Swiss-Prot : SWS_FT_FI1 15) chain B residue 175 type ACT_SITE sequence G description Proton acceptor source Swiss-Prot : SWS_FT_FI2 16) chain B residue 11 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI3 17) chain B residue 13 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3

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