|
|
eF-site ID
|
2x16-AB |
|
PDB Code
|
2x16 |
|
Chain
|
A, B |
|
click to enlarge
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|
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Title
|
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase |
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Classification
|
ISOMERASE |
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Compound
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TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL |
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Source
|
(TPIS_TRYBB) |
|
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Sequence
|
A: |
SKPQPIAAANSLSELIDLFNSTSINHDVQCVVASTFVHLA
MTKERLSHPKFVIAAQNAGNADALASLKDFGVNWIVLGHS
ERRWYYGETNEIVADKVAAAVASGFMVIACIGETLQERES
GRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAATPQQ
AQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTL
YQQRDVNGFLAGLKPEFVDIIKATQ
|
| B: |
SKPQPIAAANWKSGSPDSLSELIDLFNSTSINHDVQCVVA
STFVHLAMTKERLSHPKFVIAAQNAGNADALASLKDFGVN
WIVLGHSERRWYYGETNEIVADKVAAAVASGFMVIACIGE
TLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPV
WAIGTGKATPQQAQEAHALIRSWVSSKIGADVAGELRILY
GGSVNGKNARTLYQQRDVNGFLAGLKPEFVDIIKATQ
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Description
|
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Functional site
|
|
|
1)
|
chain |
B |
| residue |
95 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Electrophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
103 |
| type |
ACT_SITE |
| sequence |
G
|
| description |
Electrophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
167 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
11 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
B |
| residue |
11 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
B |
| residue |
13 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|