|
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eF-site ID
|
2wxv-D |
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PDB Code
|
2wxv |
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Chain
|
D |
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click to enlarge
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Title
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Structure of CDK2-CYCLIN A with a Pyrazolo(4,3-h) quinazoline-3- carboxamide inhibitor |
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Classification
|
TRANSFERASE |
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Compound
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CELL DIVISION PROTEIN KINASE 2 |
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Source
|
(CCNA2_HUMAN) |
|
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Sequence
|
D: |
PDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILV
DWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQL
VGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRME
HLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMF
LGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPES
LIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKN
SKYHGVSLLNPPETLNL
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Description
|
(1) |
CELL DIVISION PROTEIN KINASE 2 (E.C.2.7.1.37), CYCLIN-A2
|
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Functional site
|
|
|
1)
|
chain |
D |
| residue |
410 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE SO4 D 1433
|
| source |
: AC1
|
|
|
2)
|
chain |
D |
| residue |
414 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE SO4 D 1433
|
| source |
: AC1
|
|
|
|