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eF-site ID
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2wxv-B |
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PDB Code
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2wxv |
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Chain
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B |
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click to enlarge
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Title
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Structure of CDK2-CYCLIN A with a Pyrazolo(4,3-h) quinazoline-3- carboxamide inhibitor |
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Classification
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TRANSFERASE |
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Compound
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CELL DIVISION PROTEIN KINASE 2 |
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Source
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(CCNA2_HUMAN) |
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Sequence
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B: |
PDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILV
DWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQL
VGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRME
HLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMF
LGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPES
LIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKN
SKYHGVSLLNPPETLNL
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Description
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(1) |
CELL DIVISION PROTEIN KINASE 2 (E.C.2.7.1.37), CYCLIN-A2
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Functional site
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1)
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chain |
B |
| residue |
211-242 |
| type |
prosite |
| sequence |
RAILVDWLVEVGEEYKLQNETLHLAVNYIDRF
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| description |
CYCLINS Cyclins signature. RaiLvdWLvevgeeykLqnetLhlAVnYIDRF
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| source |
prosite : PS00292
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