eF-site ID 2wpa-D PDB Code 2wpa Chain D click to enlarge Title Optimisation of 6,6-Dimethyl Pyrrolo 3,4-c pyrazoles: Identification of PHA-793887, a Potent CDK Inhibitor Suitable for Intravenous Dosing Classification CELL CYCLE Compound CELL DIVISION PROTEIN KINASE 2 Source (CCNA2_HUMAN) Sequence D:  HEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWL VEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGT AAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLV LKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE LSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIR KTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKY HGVSLLNPPETLNL Description (1)  CELL DIVISION PROTEIN KINASE 2 (E.C.2.7.1.37), CYCLIN A2 Functional site 1) chain D residue 410 type sequence R description BINDING SITE FOR RESIDUE SO4 D 1433 source : AC1 2) chain D residue 414 type sequence K description BINDING SITE FOR RESIDUE SO4 D 1433 source : AC1 3) chain D residue 423 type sequence L description BINDING SITE FOR RESIDUE SO4 D 1433 source : AC1

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