eF-site ID 2wog-A
PDB Code 2wog
Chain A

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Title Intermediate and final states of human kinesin Eg5 in complex with S-trityl-L-cysteine
Classification CELL CYCLE
Compound KINESIN-LIKE PROTEIN KIF11
Source (KIF11_HUMAN)
Sequence A:  KNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGG
LADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMG
YNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGII
PRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSS
DVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEK
GAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELV
KIGKLNLVDLAGSENNINQSLLTLGRVITALVERTPHVPY
RESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLE
YAHRAKNILNKPE
Description


Functional site

1) chain A
residue 24
type
sequence R
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

2) chain A
residue 26
type
sequence R
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

3) chain A
residue 27
type
sequence P
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

4) chain A
residue 106
type
sequence Q
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

5) chain A
residue 107
type
sequence T
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

6) chain A
residue 108
type
sequence G
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

7) chain A
residue 109
type
sequence T
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

8) chain A
residue 110
type
sequence G
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

9) chain A
residue 111
type
sequence K
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

10) chain A
residue 112
type
sequence T
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

11) chain A
residue 113
type
sequence F
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

12) chain A
residue 118
type
sequence E
description BINDING SITE FOR RESIDUE ADP A 600
source : AC1

13) chain A
residue 112
type
sequence T
description BINDING SITE FOR RESIDUE MG A 601
source : AC2

14) chain A
residue 112
type
sequence T
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

15) chain A
residue 116
type
sequence E
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

16) chain A
residue 117
type
sequence G
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

17) chain A
residue 118
type
sequence E
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

18) chain A
residue 119
type
sequence R
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

19) chain A
residue 133
type
sequence A
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

20) chain A
residue 137
type
sequence P
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

21) chain A
residue 211
type
sequence Y
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

22) chain A
residue 214
type
sequence L
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

23) chain A
residue 215
type
sequence E
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

24) chain A
residue 221
type
sequence R
description BINDING SITE FOR RESIDUE ZZD A 1365
source : AC7

25) chain A
residue 105
type BINDING
sequence G
description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283
source Swiss-Prot : SWS_FT_FI1

26) chain A
residue 146
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0007744|PubMed:19608861
source Swiss-Prot : SWS_FT_FI2

27) chain A
residue 259-270
type prosite
sequence GKLNLVDLAGSE
description KINESIN_MOTOR_1 Kinesin motor domain signature. GKLnLVDLAGSE
source prosite : PS00411


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