eF-site ID 2wns-B PDB Code 2wns Chain B click to enlarge Title Human Orotate phosphoribosyltransferase (OPRTase) domain of Uridine 5' -monophosphate synthase (UMPS) in complex with its substrate orotidine 5'-monophosphate (OMP) Classification TRANSFERASE Compound OROTATE PHOSPHORIBOSYLTRANSFERASE Source (PYR5_HUMAN) Sequence B:  LGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRP RLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICS TNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVT SGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHG IRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQEAHH Description Functional site 1) chain B residue 28 type sequence L description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 2) chain B residue 29 type sequence K description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 3) chain B residue 37 type sequence Y description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 4) chain B residue 38 type sequence I description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 5) chain B residue 124 type sequence D description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 6) chain B residue 125 type sequence V description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 7) chain B residue 127 type sequence T description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 8) chain B residue 128 type sequence S description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 9) chain B residue 129 type sequence G description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 10) chain B residue 131 type sequence S description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 11) chain B residue 155 type sequence R description BINDING SITE FOR RESIDUE OMP B 550 source : AC2 12) chain B residue 80 type sequence P description BINDING SITE FOR RESIDUE CL B 1208 source : AC3 13) chain B residue 83 type sequence T description BINDING SITE FOR RESIDUE CL B 1208 source : AC3 14) chain B residue 37 type MOD_RES sequence Y description Phosphotyrosine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1

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