eF-site ID 2wmz-C PDB Code 2wmz Chain C click to enlarge Title Structure of a mutated TolC Classification MEMBRANE PROTEIN Compound OUTER MEMBRANE PROTEIN TOLC Source Escherichia coli (strain K12) (TOLC_ECOLI) Sequence C:  ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLP QLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK WRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAI DVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQ YDTVLANELTARNNLDNAVEQLRQITGNYYPELAALNVEN FKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQA QDGHLPTLDLTASTGISDTSYSGSKTRGAAGTQYDDSNMG QNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGASEQLESAH RSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEA GYSVGTSTIVDVLDATTTLYNAKQELANARYNYLINQLNI KSALGTLNEQDLLALNNALSKPVSTNPE Description Functional site 1) chain C residue 332 type sequence N description BINDING SITE FOR RESIDUE NA B 1430 source : AC4 2) chain C residue 294 type sequence Q description BINDING SITE FOR RESIDUE CL C 1429 source : AC7 3) chain C residue 296 type sequence G description BINDING SITE FOR RESIDUE CL C 1429 source : AC7 4) chain C residue 297 type sequence M description BINDING SITE FOR RESIDUE CL C 1429 source : AC7 5) chain C residue 298 type sequence V description BINDING SITE FOR RESIDUE CL C 1429 source : AC7 6) chain C residue 236 type sequence Q description BINDING SITE FOR RESIDUE PGE C 1430 source : AC8 7) chain C residue 305 type sequence A description BINDING SITE FOR RESIDUE PGE C 1430 source : AC8 8) chain C residue 308 type sequence N description BINDING SITE FOR RESIDUE PGE C 1430 source : AC8 9) chain C residue 43 type sequence G description BINDING SITE FOR RESIDUE PGE C 1431 source : AC9 10) chain C residue 1-40 type TOPO_DOM sequence ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLP description Periplasmic source Swiss-Prot : SWS_FT_FI1 11) chain C residue 75-246 type TOPO_DOM sequence IFDMSKWRALTLQEKAAGIQDVTYQTDQQTLILNTATAYF NVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDV QNARAQYDTVLANELTARNNLDNAVEQLRQITGNYYPELA ALNVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAR EQIRQAQDGHLP description Periplasmic source Swiss-Prot : SWS_FT_FI1 12) chain C residue 41-52 type TRANSMEM sequence QLGLGADYTYSN description Beta stranded; Name=S1 source Swiss-Prot : SWS_FT_FI2 13) chain C residue 53-60 type TOPO_DOM sequence GYRDANGI description Extracellular source Swiss-Prot : SWS_FT_FI3 14) chain C residue 258-278 type TOPO_DOM sequence DTSYSGSKTRGAAGTQYDDSN description Extracellular source Swiss-Prot : SWS_FT_FI3 15) chain C residue 61-74 type TRANSMEM sequence NSNATSASLQLTQS description Beta stranded; Name=S2 source Swiss-Prot : SWS_FT_FI4 16) chain C residue 247-257 type TRANSMEM sequence TLDLTASTGIS description Beta stranded; Name=S4 source Swiss-Prot : SWS_FT_FI5 17) chain C residue 279-289 type TRANSMEM sequence MGQNKVGLSFS description Beta stranded; Name=S5 source Swiss-Prot : SWS_FT_FI6

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