eF-site ID 2wmz-A PDB Code 2wmz Chain A click to enlarge Title Structure of a mutated TolC Classification MEMBRANE PROTEIN Compound OUTER MEMBRANE PROTEIN TOLC Source null (TOLC_ECOLI) Sequence A:  ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLP QLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK WRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAI DVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQ YDTVLANELTARNNLDNAVEQLRQITGNYYPELAALNVEN FKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQA QDGHLPTLDLTASTGISDTSYSGSKTRGAAGTQYDDSNMG QNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGASEQLESAH RSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEA GYSVGTSTIVDVLDATTTLYNAKQELANARYNYLINQLNI KSALGTLNEQDLLALNNALSKPVSTNPE Description Functional site 1) chain A residue 294 type sequence Q description BINDING SITE FOR RESIDUE CL A 1429 source : AC1 2) chain A residue 296 type sequence G description BINDING SITE FOR RESIDUE CL A 1429 source : AC1 3) chain A residue 297 type sequence M description BINDING SITE FOR RESIDUE CL A 1429 source : AC1 4) chain A residue 298 type sequence V description BINDING SITE FOR RESIDUE CL A 1429 source : AC1 5) chain A residue 42 type sequence L description BINDING SITE FOR RESIDUE PGE A 1430 source : AC2 6) chain A residue 43 type sequence G description BINDING SITE FOR RESIDUE PGE A 1430 source : AC2 7) chain A residue 289 type sequence S description BINDING SITE FOR RESIDUE PGE C 1431 source : AC9 8) chain A residue 1-40 type TOPO_DOM sequence ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLP description Periplasmic source Swiss-Prot : SWS_FT_FI1 9) chain A residue 75-246 type TOPO_DOM sequence IFDMSKWRALTLQEKAAGIQDVTYQTDQQTLILNTATAYF NVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDV QNARAQYDTVLANELTARNNLDNAVEQLRQITGNYYPELA ALNVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAR EQIRQAQDGHLP description Periplasmic source Swiss-Prot : SWS_FT_FI1 10) chain A residue 41-52 type TRANSMEM sequence QLGLGADYTYSN description Beta stranded; Name=S1 source Swiss-Prot : SWS_FT_FI2 11) chain A residue 53-60 type TOPO_DOM sequence GYRDANGI description Extracellular source Swiss-Prot : SWS_FT_FI3 12) chain A residue 258-278 type TOPO_DOM sequence DTSYSGSKTRGAAGTQYDDSN description Extracellular source Swiss-Prot : SWS_FT_FI3 13) chain A residue 61-74 type TRANSMEM sequence NSNATSASLQLTQS description Beta stranded; Name=S2 source Swiss-Prot : SWS_FT_FI4 14) chain A residue 247-257 type TRANSMEM sequence TLDLTASTGIS description Beta stranded; Name=S4 source Swiss-Prot : SWS_FT_FI5 15) chain A residue 279-289 type TRANSMEM sequence MGQNKVGLSFS description Beta stranded; Name=S5 source Swiss-Prot : SWS_FT_FI6

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