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eF-site ID
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2win-G |
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PDB Code
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2win |
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Chain
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G |
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click to enlarge
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Title
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C3 convertase (C3bBb) stabilized by SCIN |
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Classification
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IMMUNE SYSTEM |
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Compound
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COMPLEMENT C3 BETA CHAIN |
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Source
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ORGANISM_COMMON: HUMAN; ORGANISM_SCIENTIFIC: HOMO SAPIENS; |
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Sequence
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G: |
SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDF
PGKKLVLSSEKTVLTPATNHMGNVTFTIPANRKGRNKFVT
VQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLY
RIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLG
VLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEY
VLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEG
TAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSRKVL
LDGVQRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIV
TSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPV
AVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQ
ELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGE
TLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVRE
PGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVAD
SVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDH
GARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTP
GSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAA
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Description
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Functional site
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1)
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chain |
G |
| residue |
16 |
| type |
CARBOHYD |
| sequence |
S
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17310251, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6546754
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| source |
Swiss-Prot : SWS_FT_FI2
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2)
|
chain |
G |
| residue |
48 |
| type |
CARBOHYD |
| sequence |
S
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17310251, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6546754
|
| source |
Swiss-Prot : SWS_FT_FI2
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3)
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chain |
G |
| residue |
275 |
| type |
CARBOHYD |
| sequence |
S
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17310251, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6546754
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
|
chain |
G |
| residue |
281 |
| type |
CARBOHYD |
| sequence |
S
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17310251, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6546754
|
| source |
Swiss-Prot : SWS_FT_FI2
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