eF-site ID 2wfy-D PDB Code 2wfy Chain D click to enlarge Title Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design Classification TRANSFERASE Compound CELL DIVISION PROTEIN KINASE 2 Source Homo sapiens (Human) (2WFY) Sequence D:  NEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRA ILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGK LQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVL RMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESL AMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSW PESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREK YKNSKYHGVSLLNPPETLNL Description Functional site 1) chain D residue 210 type sequence M description BINDING SITE FOR CHAIN F OF ARG-ARG-B3L-PHE source : AC2 2) chain D residue 220 type sequence E description BINDING SITE FOR CHAIN F OF ARG-ARG-B3L-PHE source : AC2 3) chain D residue 250 type sequence R description BINDING SITE FOR CHAIN F OF ARG-ARG-B3L-PHE source : AC2 4) chain D residue 253 type sequence L description BINDING SITE FOR CHAIN F OF ARG-ARG-B3L-PHE source : AC2 5) chain D residue 254 type sequence Q description BINDING SITE FOR CHAIN F OF ARG-ARG-B3L-PHE source : AC2 6) chain D residue 281 type sequence I description BINDING SITE FOR CHAIN F OF ARG-ARG-B3L-PHE source : AC2 7) chain D residue 282 type sequence T description BINDING SITE FOR CHAIN F OF ARG-ARG-B3L-PHE source : AC2 8) chain D residue 285 type sequence T description BINDING SITE FOR CHAIN F OF ARG-ARG-B3L-PHE source : AC2

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