eF-site ID 2wfj-A PDB Code 2wfj Chain A click to enlarge Title Atomic resolution crystal structure of the PPIase domain of human cyclophilin G in complex with cyclosporin A. Classification ISOMERASE/IMMUNOSUPPRESSANT Compound PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G Source (NOR00033) Sequence A:  QRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCT GEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGR GGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFF ITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKP FAEVRILSCGEL Description (1)  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G (E.C.5.2.1.8), CYCLOSPORIN A Functional site 1) chain A residue 48 type sequence K description BINDING SITE FOR RESIDUE EDO A 1184 source : AC1 2) chain A residue 90 type sequence I description BINDING SITE FOR RESIDUE EDO A 1184 source : AC1 3) chain A residue 91 type sequence Y description BINDING SITE FOR RESIDUE EDO A 1184 source : AC1 4) chain A residue 99 type sequence S description BINDING SITE FOR RESIDUE EDO A 1184 source : AC1 5) chain A residue 86 type sequence G description BINDING SITE FOR RESIDUE CL A 1187 source : AC4 6) chain A residue 115 type sequence R description BINDING SITE FOR RESIDUE CL A 1187 source : AC4 7) chain A residue 121 type sequence G description BINDING SITE FOR RESIDUE CL A 1187 source : AC4 8) chain A residue 122 type sequence S description BINDING SITE FOR RESIDUE CL A 1187 source : AC4 9) chain A residue 123 type sequence Q description BINDING SITE FOR RESIDUE CL A 1187 source : AC4 10) chain A residue 45 type sequence T description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 11) chain A residue 46 type sequence G description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 12) chain A residue 47 type sequence E description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 13) chain A residue 49 type sequence G description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 14) chain A residue 50 type sequence T description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 15) chain A residue 67 type sequence R description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 16) chain A residue 72 type sequence F description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 17) chain A residue 75 type sequence Q description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 18) chain A residue 84 type sequence G description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 19) chain A residue 113 type sequence A description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 20) chain A residue 114 type sequence N description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 21) chain A residue 115 type sequence R description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 22) chain A residue 123 type sequence Q description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 23) chain A residue 125 type sequence F description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 24) chain A residue 133 type sequence H description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 25) chain A residue 138 type sequence H description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC5 26) chain A residue 60-77 type prosite sequence YKSCLFHRVVKDFMVQGG description CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YksClFHRVVkdFMvQGG source prosite : PS00170

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