|
|
eF-site ID
|
2wc0-F |
|
PDB Code
|
2wc0 |
|
Chain
|
F |
|
click to enlarge
|
|
|
Title
|
crystal structure of human insulin degrading enzyme in complex with iodinated insulin |
|
Classification
|
HYDROLASE/HORMONE |
|
Compound
|
INSULIN-DEGRADING ENZYME |
|
Source
|
Homo sapiens (Human) (INS_HUMAN) |
|
|
Sequence
|
F: |
FVNQHLCGSHLVEALYLVCG
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
F |
| residue |
1 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE ZN B 3012
|
| source |
: AC2
|
|
|
2)
|
chain |
F |
| residue |
7 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE DIO B 3016
|
| source |
: BC1
|
|
|
3)
|
chain |
F |
| residue |
8 |
| type |
|
| sequence |
G
|
| description |
BINDING SITE FOR RESIDUE DIO B 3016
|
| source |
: BC1
|
|
|
4)
|
chain |
F |
| residue |
9 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE DIO B 3016
|
| source |
: BC1
|
|
|
|