|
|
eF-site ID
|
2wbj-E |
|
PDB Code
|
2wbj |
|
Chain
|
E |
|
click to enlarge
|
|
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Title
|
TCR complex |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN |
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Source
|
(2WBJ) |
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|
Sequence
|
E: |
EHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVW
RLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPIT
NVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLR
NGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDC
RVEHWGLDEPLLKHWEF
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
E |
| residue |
78 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
| source |
Swiss-Prot : SWS_FT_FI10
|
|
|
2)
|
chain |
E |
| residue |
118 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
| source |
Swiss-Prot : SWS_FT_FI10
|
|
|
3)
|
chain |
E |
| residue |
49 |
| type |
BINDING |
| sequence |
G
|
| description |
BINDING => ECO:0000269|PubMed:8145819
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
E |
| residue |
52 |
| type |
BINDING |
| sequence |
A
|
| description |
BINDING => ECO:0000269|PubMed:8145819
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
E |
| residue |
53 |
| type |
SITE |
| sequence |
S
|
| description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
6)
|
chain |
E |
| residue |
55 |
| type |
SITE |
| sequence |
E
|
| description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
7)
|
chain |
E |
| residue |
62 |
| type |
SITE |
| sequence |
N
|
| description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
8)
|
chain |
E |
| residue |
69 |
| type |
SITE |
| sequence |
N
|
| description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
9)
|
chain |
E |
| residue |
76 |
| type |
SITE |
| sequence |
R
|
| description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI9
|
|
|
|