eF-site ID 2w6m-B PDB Code 2w6m Chain B click to enlarge Title Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series Classification LIGASE Compound BIOTIN CARBOXYLASE Source Escherichia coli (strain K12) (ACCC_ECOLI) Sequence B:  MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLK HVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHP GYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAI AAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKA SGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYM EKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVV EEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFE NGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQP LSIKQEEVHVRGHAVECRINAEDPNTFLPSPGKITRFHAP GGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIA RMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYL EKKLGL Description Functional site 1) chain B residue 131 type sequence V description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 2) chain B residue 159 type sequence K description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 3) chain B residue 169 type sequence M description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 4) chain B residue 201 type sequence E description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 5) chain B residue 202 type sequence K description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 6) chain B residue 203 type sequence Y description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 7) chain B residue 204 type sequence L description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 8) chain B residue 236 type sequence H description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 9) chain B residue 278 type sequence L description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 10) chain B residue 437 type sequence I description BINDING SITE FOR RESIDUE OA1 B 1446 source : AC2 11) chain B residue 292 type sequence R description BINDING SITE FOR RESIDUE CL B 1447 source : AC4 12) chain B residue 295 type sequence V description BINDING SITE FOR RESIDUE CL B 1447 source : AC4 13) chain B residue 292 type ACT_SITE sequence R description ACT_SITE => ECO:0000269|PubMed:19213731 source Swiss-Prot : SWS_FT_FI1 14) chain B residue 116 type BINDING sequence K description BINDING => ECO:0000269|PubMed:10821865, ECO:0000269|PubMed:19213731, ECO:0007744|PDB:1DV2, ECO:0007744|PDB:3G8D source Swiss-Prot : SWS_FT_FI2 15) chain B residue 165 type BINDING sequence G description BINDING => ECO:0000269|PubMed:10821865, ECO:0000269|PubMed:19213731, ECO:0007744|PDB:1DV2, ECO:0007744|PDB:3G8D source Swiss-Prot : SWS_FT_FI2 16) chain B residue 159 type BINDING sequence K description BINDING => ECO:0000269|PubMed:19213731, ECO:0007744|PDB:3G8C, ECO:0007744|PDB:3G8D source Swiss-Prot : SWS_FT_FI3 17) chain B residue 201 type BINDING sequence E description BINDING => ECO:0000269|PubMed:10821865, ECO:0000269|PubMed:19213731, ECO:0007744|PDB:1DV2, ECO:0007744|PDB:3G8C, ECO:0007744|PDB:3G8D source Swiss-Prot : SWS_FT_FI4 18) chain B residue 338 type BINDING sequence R description BINDING => ECO:0000269|PubMed:19213731, ECO:0007744|PDB:3G8C source Swiss-Prot : SWS_FT_FI5 19) chain B residue 209 type BINDING sequence H description BINDING => ECO:0000269|PubMed:19213731, ECO:0007744|PDB:3G8C source Swiss-Prot : SWS_FT_FI5 20) chain B residue 238 type BINDING sequence K description BINDING => ECO:0000269|PubMed:19213731, ECO:0007744|PDB:3G8C source Swiss-Prot : SWS_FT_FI5 21) chain B residue 292 type BINDING sequence R description BINDING => ECO:0000269|PubMed:19213731, ECO:0007744|PDB:3G8C source Swiss-Prot : SWS_FT_FI5 22) chain B residue 295 type BINDING sequence V description BINDING => ECO:0000269|PubMed:19213731, ECO:0007744|PDB:3G8C source Swiss-Prot : SWS_FT_FI5 23) chain B residue 236 type BINDING sequence H description BINDING => ECO:0000269|PubMed:10821865, ECO:0000269|PubMed:19213731, ECO:0007744|PDB:1DV2, ECO:0007744|PDB:3G8C source Swiss-Prot : SWS_FT_FI6 24) chain B residue 276 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU00409 source Swiss-Prot : SWS_FT_FI7 25) chain B residue 288 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU00409 source Swiss-Prot : SWS_FT_FI7 26) chain B residue 290 type BINDING sequence N description BINDING => ECO:0000255|PROSITE-ProRule:PRU00409 source Swiss-Prot : SWS_FT_FI7

Display surface Download Links